Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Infant respiratory infections and later respiratory hospitalisation in childhood

    Access Status
    Open access via publisher
    Authors
    Moore, H.
    Hall, Graham
    De Klerk, N.
    Date
    2015
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Moore, H. and Hall, G. and De Klerk, N. 2015. Infant respiratory infections and later respiratory hospitalisation in childhood. European Respiratory Journal. 46 (5): pp. 1334-1341.
    Source Title
    European Respiratory Journal
    DOI
    10.1183/13993003.00587-2015
    ISSN
    0903-1936
    School
    School of Physiotherapy and Exercise Science
    URI
    http://hdl.handle.net/20.500.11937/55017
    Collection
    • Curtin Research Publications
    Abstract

    Acute respiratory infections (ARI) cause significant morbidity in infancy. We sought to quantify the relationship between ARI and development of respiratory morbidity in early childhood. Population-based longitudinal hospitalisation data were linked to perinatal, birth and death records for 145 580 Western Australian children from 1997 to 2002. We conducted Cox regression with sensitivity analyses to quantify the risk of recurrent ARI in infancy for respiratory hospitalisation after the age of 3 years. ARI in infancy was significantly related to respiratory hospitalisation before (hazard ratio (HR) 3.5, 95% CI 3.1–3.8) and after (HR 3.0, 95% CI 2.6–3.4) adjusting for known risk factors including maternal smoking during pregnancy, season of birth, delivery mode and gestational age. We noted a dose response with the number and length of infant ARI hospitalisations and increasing risk with no effect modification by gestational age. Results were similar when later respiratory hospitalisations were restricted to asthma hospitalisations only. Recurrent hospitalisations for ARI in infancy significantly increase the risk of respiratory morbidity and asthma requiring hospitalisation after the age of 3 years in a dose-response fashion. The increase in relative risk is not modified by gestational age. Efforts to reduce the occurrence of infant ARI are likely to have significant public health benefits.

    Related items

    Showing items related by title, author, creator and subject.

    • Comparison between Nasal Swabs and Nasopharyngeal Aspirates for, and Effect of Time in Transit on, Isolation of Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and Moraxella catarrhalis
      Carville, K.; Bowman, J.; Lehmann, Deborah; Riley, T. (2007)
      pmc logo image Logo of jcm Note: Performing your original search, comparison nasal swabs lehmann, in PubMed Central will retrieve 7 citations. Journal List > J Clin Microbiol > v.45(1); Jan 2007 Abstract ...
    • Respiratory viral infections in Western Australians with cystic fibrosis
      Brestovac, Brian ; Lawrence, Charleigh; Speers, D.J.; Sammels, L.M.; Mulrennan, S. (2020)
      Background: Viral respiratory infections (VRI) in people living with Cystic fibrosis (CF) is less well understood than respiratory bacterial infections, particularly adults with CF and few studies have compared children ...
    • Indoor air quality, house characteristics and respiratory symptoms among mothers and children in Tamil Nadu State, India
      Kandiah, Morgan Dharmaratnam (2010)
      Air pollution is a problem affecting developing and developed countries concerned about the adverse health effects associated with exposure to indoor and outdoor air pollutants. In developing countries like India, the ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.