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    Comparison of relationships between four common anthropometric measures and incident diabetes

    Access Status
    Fulltext not available
    Authors
    Lee, Crystal
    Woodward, M.
    Pandeya, N.
    Adams, R.
    Barrett-Connor, E.
    Boyko, E.
    Eliasson, M.
    Franco, L.
    Fujimoto, W.
    Gonzalez, C.
    Howard, B.
    Jacobs, D.
    Keinanen-Kiukaanniemi, S.
    Magliano, D.
    Schreiner, P.
    Shaw, J.
    Stevens, J.
    Taylor, A.
    Tuomilehto, J.
    Wagenknecht, L.
    Huxley, Rachel
    Date
    2017
    Type
    Journal Article
    
    Metadata
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    Citation
    Lee, C. and Woodward, M. and Pandeya, N. and Adams, R. and Barrett-Connor, E. and Boyko, E. and Eliasson, M. et al. 2017. Comparison of relationships between four common anthropometric measures and incident diabetes. Diabetes Research and Clinical Practice. 132: pp. 36-44.
    Source Title
    Diabetes Research and Clinical Practice
    DOI
    10.1016/j.diabres.2017.07.022
    ISSN
    0168-8227
    School
    School of Public Health
    URI
    http://hdl.handle.net/20.500.11937/55403
    Collection
    • Curtin Research Publications
    Abstract

    © 2017 Elsevier B.V. Aims First, to conduct a detailed exploration of the prospective relations between four commonly used anthropometric measures with incident diabetes and to examine their consistency across different population subgroups. Second, to compare the ability of each of the measures to predict five-year risk of diabetes. Methods We conducted a meta-analysis of individual participant data on body mass index (BMI), waist circumference (WC), waist-hip and waist-height ratio (WHtR) from the Obesity, Diabetes and Cardiovascular Disease Collaboration. Cox proportional hazard models were used to estimate the association between a one standard deviation increment in each anthropometric measure and incident diabetes. Harrell's concordance statistic was used to test the predictive accuracy of each measure for diabetes risk at five years. Results Twenty-one studies with 154,998 participants and 9342 cases of incident diabetes were available. Each of the measures had a positive association with incident diabetes. A one standard deviation increment in each of the measures was associated with 64–80% higher diabetes risk. WC and WHtR more strongly associated with risk than BMI (ratio of hazard ratios: 0.95 [0.92,0.99] – 0.97 [0.95,0.98] ) but there was no appreciable difference between the four measures in the predictive accuracy for diabetes at five years. Conclusions Despite suggestions that abdominal measures of obesity have stronger associations with incident diabetes and better predictive accuracy than BMI, we found no overall advantage in any one measure at discriminating the risk of developing diabetes. Any of these measures would suffice to assist in primary diabetes prevention efforts.

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