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dc.contributor.authorElaskalani, O.
dc.contributor.authorRazak, N.
dc.contributor.authorFalasca, Marco
dc.contributor.authorMetharom, Pat
dc.date.accessioned2017-09-27T10:20:33Z
dc.date.available2017-09-27T10:20:33Z
dc.date.created2017-09-27T09:48:04Z
dc.date.issued2017
dc.identifier.citationElaskalani, O. and Razak, N. and Falasca, M. and Metharom, P. 2017. Epithelial-mesenchymal transition as a therapeutic target for overcoming chemoresistance in pancreatic cancer. WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY. 9 (1): pp. 37-41.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/56690
dc.identifier.doi10.4251/wjgo.v9.i1.37
dc.description.abstract

Pancreatic cancer has one of the worst prognoses among all cancers due to the late manifestation of identifiable symptoms and high resistance to chemo- and radiation therapies. In recent years, a cancer development phase termed epithelial-mesenchymal transition (EMT) has gained increasing research focus. The process is implicated in tumour metastasis, and emerging evidence suggests EMT also contributes or induces chemoresistance in several cancers. Nevertheless, the applicability of therapeutic targeting of EMT faces many challenges. In this mini-review, we summarise the evidence supporting the role of EMT in pancreatic cancer progression, focusing particularly on its association with chemoresistance.

dc.publisherBAISHIDENG PUBLISHING GROUP INC
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.rights.uri
dc.titleEpithelial-mesenchymal transition as a therapeutic target for overcoming chemoresistance in pancreatic cancer
dc.typeJournal Article
dcterms.source.volume9
dcterms.source.number1
dcterms.source.startPage37
dcterms.source.endPage41
dcterms.source.issn1948-5204
dcterms.source.titleWORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY
curtin.departmentSchool of Biomedical Sciences
curtin.accessStatusOpen access


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