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dc.contributor.authorMcKetin, Rebecca
dc.contributor.authorNajman, J.
dc.contributor.authorBaker, A.
dc.contributor.authorLubman, D.
dc.contributor.authorDawe, S.
dc.contributor.authorAli, R.
dc.contributor.authorLee, N.
dc.contributor.authorMattick, R.
dc.contributor.authorMamun, A.
dc.identifier.citationMcKetin, R. and Najman, J. and Baker, A. and Lubman, D. and Dawe, S. and Ali, R. and Lee, N. et al. 2012. Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES). Addiction. 107 (11): pp. 1998-2008.

Aims: To evaluate the impact of community-based drug treatment on methamphetamine use using inverse probability of treatment-weighted (IPTW) estimators to derive treatment effects. Design: A longitudinal prospective cohort study with follow-ups at 3 months, 1 year and 3 years. Treatment effects were derived by comparing groups at follow-up. IPTW estimators were used to adjust for pre-treatment differences between groups. Setting: Sydney and Brisbane, Australia. Participants: Participants were methamphetamine users entering community-based detoxification (n=112) or residential rehabilitation (n=248) services and a quasi-control group of methamphetamine users (n=101) recruited from the community. Measurements: Frequency of methamphetamine use between interviews (no use, less than weekly, 1-2 days per week, 3+ days per week), continuous abstinence from methamphetamine use, past month methamphetamine use and methamphetamine dependence. Findings: Detoxification did not reduce methamphetamine use at any follow-up relative to the quasi-control group. Relative to quasi-control and detoxification groups combined, residential rehabilitation produced large reductions in the frequency of methamphetamine use at 3 months [odds ratio (OR)=0.23, 95% confidence interval (CI) 0.15-0.36, P < 0.001), with a marked attenuation of this effect at 1 year (OR 0.62, 95% CI 0.40-0.97, P=0.038) and 3 years (OR=0.71, 95% CI 0.42-1.19, P=0.189). The greatest impact was for abstinence: for every 100 residential rehabilitation clients there was a gain of 33 being continuously abstinent at 3 months, with this falling to 14 at 1 year and 6 at 3 years. Conclusions: Community-based residential rehabilitation may produce a time-limited decrease in methamphetamine use, while detoxification alone does not appear to do so.

dc.publisherWiley-Blackwell Publishing Ltd.
dc.titleEvaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES)
dc.typeJournal Article
curtin.departmentNational Drug Research Institute (NDRI)
curtin.accessStatusFulltext not available

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