Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES)
|dc.identifier.citation||McKetin, R. and Najman, J. and Baker, A. and Lubman, D. and Dawe, S. and Ali, R. and Lee, N. et al. 2012. Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES). Addiction. 107 (11): pp. 1998-2008.|
Aims: To evaluate the impact of community-based drug treatment on methamphetamine use using inverse probability of treatment-weighted (IPTW) estimators to derive treatment effects. Design: A longitudinal prospective cohort study with follow-ups at 3 months, 1 year and 3 years. Treatment effects were derived by comparing groups at follow-up. IPTW estimators were used to adjust for pre-treatment differences between groups. Setting: Sydney and Brisbane, Australia. Participants: Participants were methamphetamine users entering community-based detoxification (n=112) or residential rehabilitation (n=248) services and a quasi-control group of methamphetamine users (n=101) recruited from the community. Measurements: Frequency of methamphetamine use between interviews (no use, less than weekly, 1-2 days per week, 3+ days per week), continuous abstinence from methamphetamine use, past month methamphetamine use and methamphetamine dependence. Findings: Detoxification did not reduce methamphetamine use at any follow-up relative to the quasi-control group. Relative to quasi-control and detoxification groups combined, residential rehabilitation produced large reductions in the frequency of methamphetamine use at 3 months [odds ratio (OR)=0.23, 95% confidence interval (CI) 0.15-0.36, P < 0.001), with a marked attenuation of this effect at 1 year (OR 0.62, 95% CI 0.40-0.97, P=0.038) and 3 years (OR=0.71, 95% CI 0.42-1.19, P=0.189). The greatest impact was for abstinence: for every 100 residential rehabilitation clients there was a gain of 33 being continuously abstinent at 3 months, with this falling to 14 at 1 year and 6 at 3 years. Conclusions: Community-based residential rehabilitation may produce a time-limited decrease in methamphetamine use, while detoxification alone does not appear to do so.
|dc.publisher||Wiley-Blackwell Publishing Ltd.|
|dc.title||Evaluating the impact of community-based treatment options on methamphetamine use: Findings from the Methamphetamine Treatment Evaluation Study (MATES)|
|curtin.department||National Drug Research Institute (NDRI)|
|curtin.accessStatus||Fulltext not available|
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