Curtin University Homepage
  • Library
  • FAQ
    • Log in

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Short-term training alters the control of mitochondrial respiration rate before maximal oxidative ATP synthesis

    Access Status
    Fulltext not available
    Authors
    Layec, G.
    Haseler, Luke
    Hoff, J.
    Hart, C.
    Liu, X.
    Le Fur, Y.
    Jeong, E.
    Richardson, R.
    Date
    2013
    Collection
    • Curtin Research Publications
    Type
    Journal Article
    Metadata
    Show full item record
    Abstract

    Aim: Short-term exercise training may induce metabolic and performance adaptations before any changes in mitochondrial enzyme potential. However, there has not been a study that has directly assessed changes in mitochondrial oxidative capacity or metabolic control as a consequence of such training in vivo. Therefore, we used 31 P-magnetic resonance spectroscopy ( 31 P-MRS) to examine the effect of short-term plantar flexion exercise training on phosphocreatine (PCr) recovery kinetics and the control of respiration rate. Method: To this aim, we investigated 12 healthy men, experienced with this exercise modality (TRA), and 7 time-control subjects (TC). Results: After 5 days of training, maximum work rate during incremental plantar flexion exercise was significantly improved (P < 0.01). During the recovery period, the maximal rate of oxidative adenosine triphosphate synthesis (PRE: 28 ± 13 mm min -1 ; POST: 26 ± 15 mm min -1 ) and the PCr recovery time constant (PRE: 31 ± 19 s; POST: 29 ± 16) were not significantly altered. In contrast, the Hill coefficient (n H ) describing the co-operativity between respiration rate and ADP was significantly increased in TRA (PRE: n H = 2.7 ± 1.4; POST: n H = 3.4 ± 1.9, P < 0.05). Meanwhile, there were no systematic variations in any of these variables in TC. Conclusion: This study reveals that 5 days of training induces rapid adaptation in the allosteric control of respiration rate by ADP before any substantial improvement in muscle oxidative capacity occurs. © 2013 Scandinavian Physiological Society.

    Citation
    Layec, G. and Haseler, L. and Hoff, J. and Hart, C. and Liu, X. and Le Fur, Y. and Jeong, E. et al. 2013. Short-term training alters the control of mitochondrial respiration rate before maximal oxidative ATP synthesis. Acta Physiologica. 208 (4): pp. 376-386.
    Source Title
    Acta Physiologica
    URI
    http://hdl.handle.net/20.500.11937/58360
    DOI
    10.1111/apha.12103
    Department
    School of Physiotherapy and Exercise Science

    Related items

    Showing items related by title, author, creator and subject.

    • Burden of disease and benefits of exercise in fixed airway obstruction asthma
      Turner, Sian Elizabeth (2009)
      Background and research questions. The characterization of chronic persistent asthma in an older adult population is not well defined. This is due to the difficulties in separating the diagnosis of asthma from that of ...
    • The effectiveness of session rating of perceived exertion to monitor resistance training load in acute burns patients
      Grisbrook, Tiffany; Gittings, P.; Wood, F.; Edgar, D. (2016)
      Session-rating of perceived exertion (RPE) is a method frequently utilised in exercise and sports science to quantify training load of an entire aerobic exercise session. It has also been demonstrated that session-RPE is ...
    • Exercise and vascular adaptation in asymptomatic humans
      Green, D.; Spence, Angela; Halliwill, J.; Cable, N.T.; Thijssen, D. (2011)
      Beneficial effects of exercise training on the vasculature have been consistently reported in subjects with cardiovascular risk factors or disease, whereas studies in apparently healthy subjects have been less uniform. ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorsTitlesSubjectsDocument TypesThis CollectionIssue DateAuthorsTitlesSubjectsDocument Types

    My Account

    Log in

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Connect with Curtin

    • 
    • 
    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Send FeedbackContact Us
    DSpace software copyright © 2002-2015  DuraSpace