Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Midterm outcome after aortic root replacement with stentless porcine bioprostheses

    Access Status
    Open access via publisher
    Authors
    Ennker, I.
    Albert, A.
    Dalladaku, F.
    Rosendahl, U.
    Ennker, J.
    Florath, Ines
    Date
    2011
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Ennker, I. and Albert, A. and Dalladaku, F. and Rosendahl, U. and Ennker, J. and Florath, I. 2011. Midterm outcome after aortic root replacement with stentless porcine bioprostheses. European Journal of Cardio-thoracic Surgery. 40 (2): pp. 429-434.
    Source Title
    European Journal of Cardio-thoracic Surgery
    DOI
    10.1016/j.ejcts.2010.12.010
    ISSN
    1010-7940
    School
    Epidemiology and Biostatistics
    URI
    http://hdl.handle.net/20.500.11937/5902
    Collection
    • Curtin Research Publications
    Abstract

    Objective: Midterm clinical outcome was evaluated after aortic root replacement with Freestyle ® stentless aortic root bioprostheses. Methods: Between April 1996 and December 2007, 301 patients underwent aortic valve replacement with stentless Medtronic Freestyle ® bioprostheses in full-root technique at a single center. Concomitant coronary artery bypass grafting (CABG) was required in 96 patients (32%). In 94 patients (31%), the ascending aorta was replaced. The mean age was 71.6±9.1 (range: 36-89) years. Follow-up was closed in October 2008, 99% complete and encompassed 916 patient-years. Results: Overall mortality within 30 days was 5%. A total of 62 patients died during the follow-up period. Overall survival at 5 and 9 years was 74±4% and 53±6%, respectively. Re-operations were required in three patients: in one patient due to structural valve deterioration, and in two patients due to prosthetic valve endocarditis. Non-structural dysfunctions were not observed. In eight patients, prosthetic valve endocarditis occurred, in most of them (N=6) during the first year after surgery. Rate of freedom from re-operation, structural valve deterioration, prosthetic valve endocarditis, thrombo-embolic and major bleeding events at 9 years was 94±6%, 94±6%, 94±3%, 87±5%, and 95±2%, respectively. The linearized rates of late adverse events in percent per patient-year were 0.35, 0.12, 0.83, 1.7, and 0.7, respectively, for re-operation, structural valve deterioration, prosthetic valve endocarditis, thrombo-embolic and major bleeding events. A little less than a quarter (22%) of the patients required anticoagulation therapy. Conclusions: Aortic root replacement with the stentless Freestyle ® bioprosthesis provided a respectable short-term mortality, optimal valve durability and acceptable rates of valve-related complications within 9 years.

    Related items

    Showing items related by title, author, creator and subject.

    • Ten-Year Experience With Stentless Aortic Valves: Full-Root Versus Subcoronary Implantation
      Ennker, J.; Albert, A.; Rosendahl, U.; Ennker, I.; Dalladaku, F.; Florath, Ines (2008)
      Background: We compared the midterm outcome after aortic valve replacement with the Freestyle stentless bioprosthesis for the full-root or subcoronary implantation technique, while adjusting for patient and disease ...
    • The freestyle stentless bioprosthesis in more than 1000 patients: A single-center experience over 10 years
      Ennker, J.; Ennker, I.; Albert, A.; Rosendahl, U.; Bauer, S.; Florath, Ines (2009)
      Background and Aim: Early and mid-term clinical outcomes after aortic valve replacement (AVR) with stentless bioprostheses in a large cohort of patients are presented. Methods: Between April 1996 and November 2005, 1014 ...
    • Cerebrovascular Events After Stentless Aortic Valve Replacement During a 9-Year Follow-Up Period
      Gulbins, H.; Florath, Ines; Ennker, J. (2008)
      Background: One major advantage of biologic aortic valve prostheses is their low thrombogenicity compared with mechanical prostheses. The purpose of this study was to evaluate the incidence of cerebrovascular events during ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.