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dc.contributor.authorHirvikoski, T.
dc.contributor.authorMittendorfer-Rutz, E.
dc.contributor.authorBoman, M.
dc.contributor.authorLarsson, H.
dc.contributor.authorLichtenstein, P.
dc.contributor.authorBölte, Sven
dc.identifier.citationHirvikoski, T. and Mittendorfer-Rutz, E. and Boman, M. and Larsson, H. and Lichtenstein, P. and Bölte, S. 2016. Premature mortality in autism spectrum disorder. British Journal of Psychiatry. 208 (3): pp. 232-238.

Background: Mortality has been suggested to be increased in autism spectrum disorder (ASD). Aims: To examine both all-cause and cause-specific mortality in ASD, as well as investigate moderating role of gender and intellectual ability. Method: Odds ratios (ORs) were calculated for a population-based cohort of ASD probands (n = 27 122, diagnosed between 1987 and 2009) compared with gender-, age-and county of residence-matched controls (n = 2 672 185). Results: During the observed period, 24 358 (0.91%) individuals in the general population died, whereas the corresponding figure for individuals with ASD was 706 (2.60%; OR = 2.56; 95% CI 2.38-2.76). Cause-specific analyses showed elevated mortality in ASD for almost all analysed diagnostic categories. Mortality and patterns for cause-specific mortality were partly moderated by gender and general intellectual ability. Conclusions: Premature mortality was markedly increased in ASD owing to a multitude of medical conditions.

dc.publisherRoyal College of Psychiatrists
dc.titlePremature mortality in autism spectrum disorder
dc.typeJournal Article
dcterms.source.titleBritish Journal of Psychiatry
curtin.departmentSchool of Occupational Therapy and Social Work
curtin.accessStatusOpen access via publisher

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