Training-induced plasticity of the social brain in autism spectrum disorder
MetadataShow full item record
Background: Autism spectrum disorder (ASD) is linked to social brain activity and facial affect recognition (FAR). Aims: To examine social brain plasticity in ASD. Method: Using FAR tests and functional magnetic resonance imaging tasks for FAR, we compared 32 individuals with ASD and 25 controls. Subsequently, the participants with ASD were assigned to FAR computer-aided cognitive training or a control group. Results: The ASD group performed more poorly than controls on explicit behavioural FAR tests. In the scanner, during implicit FAR, the amygdala, fusiform gyrus and other regions of the social brain were less activated bilaterally. The training group improved on behavioural FAR tests, and cerebral response to implicit affect processing tasks increased bilaterally post-training in the social brain. Conclusions: Individuals with ASD show FAR impairments associated with hypoactivation of the social brain. Computer-based training improves explicit FAR and neuronal responses during implicit FAR, indicating neuroplasticity in the social brain in ASD.
Showing items related by title, author, creator and subject.
Evidence-based evaluation of programme interventions to achieve positive community integration outcomes for adults with acquired brain injuryParvaneh, Shahriar (2010)Background. The growing population of people with acquired brain injury (ABI) requires a strong focus on clients to be integrated into the community in order to use their productive skills in society, to help them live ...
Mitii™ ABI: Study protocol of a randomised controlled trial of a web-based multi-modal training program for children and adolescents with an Acquired Brain Injury (ABI)Boyd, Roslyn; Baque, E.; Piovesana, A.; Ross, S.; Ziviani, J.; Sakzewski, L.; Barber, L.; Lloyd, O.; McKinlay, L.; Whittingham, K.; Smith, A.; Rose, S.; Fiori, S.; Cunnington, R.; Ware, R.; Lewis, M.; Comans, T.; Scuffham, P. (2015)© 2015 Boyd et al. Background: Acquired brain injury (ABI) refers to multiple disabilities arising from damage to the brain acquired after birth. Children with an ABI may experience physical, cognitive, social and ...
Enhancing Cognitive Functioning in Healthly Older Adults: a Systematic Review of the Clinical Significance of Commercially Available Computerized Cognitive Training in Preventing Cognitive DeclineShah, T.; Weinborn, M.; Verdile, Giuseppe; Sohrabi, H.; Martins, R. (2017)Successfully assisting older adults to maintain or improve cognitive function, particularly when they are dealing with neurodegenerative disorders such as Alzheimer’s disease (AD), remains a major challenge. Cognitive ...