Host-multi pathogen-warfare: Pathogen interactions in co-infected plants
MetadataShow full item record
Studies of plant–pathogen interactions have historically focused on simple models of infection involving single host-single disease systems. However, plant infections often involve multiple species and/or genotypes and exhibit complexities not captured in single host-single disease systems. Here, we review recent insights into co-infection systems focusing on the dynamics of host-multi-pathogen interactions and the implications for host susceptibility/resistance. In co-infection systems, pathogen interactions include: (i) Competition, in which competing pathogens develop physical barriers or utilize toxins to exclude competitors from resource-dense niches; (ii) Cooperation, whereby pathogens beneficially interact, by providing mutual biochemical signals essential for pathogenesis, or through functional complementation via the exchange of resources necessary for survival; (iii) Coexistence, whereby pathogens can stably coexist through niche specialization. Furthermore, hosts are also able to, actively or passively, modulate niche competition through defense responses that target at least one pathogen. Typically, however, virulent pathogens subvert host defenses to facilitate infection, and responses elicited by one pathogen may be modified in the presence of another pathogen. Evidence also exists, albeit rare, of pathogens incorporating foreign genes that broaden niche adaptation and improve virulence. Throughout this review, we draw upon examples of co-infection systems from a range of pathogen types and identify outstanding questions for future innovation in disease control strategies.
Showing items related by title, author, creator and subject.
Real-time PCR for diagnosing and quantifying co-infection by two globally distributed fungal pathogens of wheatAbdullah, A.; Turo, C.; Moffat, Caroline; Lopez-Ruiz, Fran; Gibberd, Mark; Hamblin, J.; Zerihun, Ayalsew (2018)Co-infections – invasions of a host-plant by multiple pathogen species or strains – are common, and are thought to have consequences for pathogen ecology and evolution. Despite their apparent significance, co-infections ...
Young, S.; Carrel, M.; Malanson, G.; Ali, Mohammed; Kayali, G. (2016)© 2016 by the authors; licensee MDPI, Basel, Switzerland. Human outbreaks with avian influenza have been, so far, constrained by poor viral adaptation to non-avian hosts. This could be overcome via co-infection, whereby ...
Abdullah, Araz Sedqi (2019)This PhD bridges the gap between the heterogeneity of plant diseases in the field and the emerging field of molecular pathology. It uses a three-way system consisting of the wheat host and two fungi. A range of techniques ...