Osteogenic effects of a physical activity intervention in South African black children
|dc.identifier.citation||Meiring, R. and Micklesfield, L. and Avidon, I. and McVeigh, J. 2014. Osteogenic effects of a physical activity intervention in South African black children. Journal of Musculoskeletal Neuronal Interactions. 14 (3): pp. 276-285.|
Objectives: To determine whether a weight-bearing physical activity intervention improves measures of bone density, size and strength in a pre- and early pubertal cohort of black South African children. Methods: Twenty two school children (9.7±1.1 years) were cluster randomised into an exercise (EX; n=12) and control (CON; n=10) group. EX children performed a weight-bearing exercise program for 20 weeks. CON children continued their regular activities. Whole body DXA and tibial peripheral QCT scans were obtained. Urine was analysed for concentrations of cross-linked N-telopeptides of Type I collagen (NTX).Results: Changes in 4% volumetric BMD, area and strength were greater in EX than CON. At the 38% site, change in bone area and density was greater in EX than CON. The greater change in periosteal circumference in the EX groups also resulted in a greater change in cortical thickness of the tibia compared to the CON group. NTX concentration was lower in the EX group than the CON group after the intervention. Conclusions: This study documents for the first time the beneficial response of trabecular and cortical bone of black children to a weight bearing exercise intervention.
|dc.title||Osteogenic effects of a physical activity intervention in South African black children|
|dcterms.source.title||Journal of Musculoskeletal Neuronal Interactions|
|curtin.department||School of Occupational Therapy and Social Work|
|curtin.accessStatus||Fulltext not available|
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