Neural mechanisms of savant calendar calculating in autism: An MEG-study of few single cases
MetadataShow full item record
This study contrasted the neurological correlates of calendar calculating (CC) between those individuals with autism spectrum disorder (ASD) and typically developing individuals. CC is the ability to correctly and quickly state the day of the week of a given date. Using magnetoencephalography (MEG), we presented 126 calendar tasks with dates of the present, past, and future. Event-related magnetic fields (ERF) of 3000. ms duration and brain activation patterns were compared in three savant calendar calculators with ASD (ASDCC) and three typically developing calendar calculators (TYPCC). ASDCC outperformed TYPCC in correct responses, but not in answering speed. Comparing amplitudes of their ERFs, there was a main effect of group between 1000 and 3000. ms, but no further effects of hemisphere or sensor location. We conducted CLARA source analysis across the entire CC period in each individual. Both ASDCC and TYPCC exhibited activation maxima in prefrontal areas including the insulae and the left superior temporal gyrus. This is in accordance with verbal fact retrieval and working memory as well as monitoring and coordination processes. In ASDCC, additional activation sites at the right superior occipital gyrus, the right precuneus, and the right putamen point to visual-spatial strategies and are in line with the preference of autistic individuals for engaging posterior regions relatively more strongly in various reasoning and problem solving tasks. © 2014 Elsevier Inc.
Showing items related by title, author, creator and subject.
Episodic Neoglacial snowline descent and glacier expansion on Svalbard reconstructed from the <sup>14</sup>C ages of ice-entombed plantsMiller, Gifford; Landvik, J.; Lehman, S.; Southon, J. (2017)The response of the Northern Hemisphere cryosphere to the monotonic decline in summer insolation and variable radiative forcing during the Holocene has been one of irregular expansion culminating in the Little Ice Age, ...
Increased mortality among Indigenous persons during and after release from prison in New South WalesKariminia, A.; Butler, Tony; Jones, J.; Law, M. (2012)Objective: To estimate the overall and cause specific mortality of Aboriginal offenders in New South Wales (NSW), Australia. Methods: The study cohort consisted of all Aboriginal men and women aged 18 years and older who ...
Koye, D.; Magliano, D.; Reid, Christopher; Pavkov, M.; Chadban, S.; McDonald, S.; Polkinghorne, K.; White, S.; Paul, C.; Shaw, J. (2018)RATIONALE & OBJECTIVE: The number of people with diabetes and end-stage kidney disease (ESKD) is increasing worldwide, but it is unknown whether this indicates an increasing risk for ESKD in people with diabetes. We ...