Structural requirements for anti-oxidant activity of calix[n]arenes and their associated anti-bacterial activity
Access Status
Open access
Authors
Stephens, E.
Tauran, Y.
Coleman, A.
Fitzgerald, Melinda
Date
2015Type
Journal Article
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Stephens, E. and Tauran, Y. and Coleman, A. and Fitzgerald, M. 2015. Structural requirements for anti-oxidant activity of calix[n]arenes and their associated anti-bacterial activity. Chemical Communications. 51 (5): pp. 851-854.
Source Title
Chemical Communications
ISSN
School
Health Sciences Research and Graduate Studies
Collection
Abstract
Treatment of neural cells with calix[n]arenes featuring sulphonate moieties and linked to Ag nanoparticles results in reduced reactive species. For gram+ bacteria there is an inverse correlation between anti-bacterial activity and ROS reduction whereas for gram- bacteria only calix[6]arenes bearing O-alkyl sulphonate functions act as ROS inhibitors and anti-bacterial agents.
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