Distribution and diversity of bacterial secretion systems across metagenomic datasets
MetadataShow full item record
Bacteria can manipulate their surrounding environment through the secretion of proteins into other living organisms and into the extracellular milieu. In Gram stain negative bacteria this process is mediated by different types of secretion systems from type I through type VI secretion system (T1SS–T6SS). In this study the prevalence of these secretion systems in 312 publicly available microbiomes derived from a wide range of ecosystems was investigated by a gene-centric approach. Our analysis demonstrates that some secretion systems are over-represented in some specific samples. In addition, some T3SS and T6SS phylogenetic clusters were specifically enriched in particular ecological niches, which could indicate specific bacterial adaptation to these environments.
Showing items related by title, author, creator and subject.
Liu, Lifang; Feizi, A.; Österlund, T.; Hjort, C.; Nielsen, J. (2014)Background: The koji mold, Aspergillus oryzae is widely used for the production of industrial enzymes due to its particularly high protein secretion capacity and ability to perform post-translational modifications. However, ...
High-quality permanent draft genome sequence of the Bradyrhizobium elkanii type strain USDA 76<sup>T</sup>, isolated from Glycine max (L.) MerrReeve, W.; van Berkum, P.; Ardley, J.; Tian, R.; Gollagher, M.; Marinova, Dora; Elia, P.; Reddy, T.; Pillay, M.; Varghese, N.; Seshadri, R.; Ivanova, N.; Woyke, T.; Baeshen, M.; Baeshen, N.; Kyrpides, N. (2017)Â© 2017 The Author(s). Bradyrhizobium elkanii USDA 76 T (INSCD = ARAG00000000), the type strain for Bradyrhizobium elkanii, is an aerobic, motile, Gram-negative, non-spore-forming rod that was isolated from an effective ...
Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetesSolimena, Michele; Schulte, A.; Marselli, L.; Ehehalt, F.; Richter, D.; Kleeberg, M.; Mziaut, H.; Knoch, K.; Parnis, J.; Bugliani, M.; Siddiq, A.; Jörns, A.; Burdet, F.; Liechti, R.; Suleiman, M.; Margerie, D.; Syed, F.; Distler, M.; Grützmann, R.; Petretto, E.; Moreno-Moral, A.; Wegbrod, C.; Sönmez, A.; Pfriem, K.; Friedrich, A.; Meinel, J.; Wollheim, C.; Baretton, G.; Scharfmann, R.; Nogoceke, E.; Bonifacio, E.; Sturm, D.; Meyer-Puttlitz, B.; Boggi, U.; Saeger, H.; Filipponi, F.; Lesche, M.; Meda, P.; Dahl, A.; Wigger, L.; Xenarios, I.; Falchi, M.; Thorens, B.; Weitz, J.; Bokvist, K.; Lenzen, S.; Rutter, G.; Froguel, P.; von Bülow, M.; Ibberson, M.; Marchetti, P. (2018)© 2017, The Author(s). Aims/hypothesis: Pancreatic islet beta cell failure causes type 2 diabetes in humans. To identify transcriptomic changes in type 2 diabetic islets, the Innovative Medicines Initiative for Diabetes: ...