Measurement of coronary bifurcation angle with coronary CT angiography: A phantom study
Embargo Lift Date
MetadataShow full item record
© 2017 Associazione Italiana di Fisica Medica. Purpose: Accurate determination of the bifurcation angle and correlation with plaque buildup may lead to the prediction of coronary artery disease (CAD). This work evaluates two techniques to measure bifurcation angles in 3D space using coronary computed tomography angiography (CCTA). Materials and Methods: Nine phantoms were fabricated with different bifurcation angles ranging from 55.3° to 134.5°. General X-ray and CCTA were employed to acquire 2D and 3D images of the bifurcation phantoms, respectively. Multiplanar reformation (MPR) and volume rendering technique (VRT) were used to measure the bifurcation angle between the left anterior descending (LAD) and left circumflex arteries (LCx). The measured angles were compared with the true values to determine the accuracy of each measurement technique. Inter-observer variability was evaluated. The two techniques were further applied on 50 clinical CCTA cases to verify its clinical value. Results: In the phantom setting, the mean absolute differences calculated between the true and measured angles by MPR and VRT were 2.4°. ±. 2.2° and 3.8°. ±. 2.9°, respectively. Strong correlation was found between the true and measured bifurcation angles. Furthermore, no significant differences were found between the bifurcation angles measured using either technique. In clinical settings, large difference of 12.0°. ±. 10.6° was found between the two techniques. Conclusion: In the phantom setting, both techniques demonstrated a significant correlation to the true bifurcation angle. Despite the lack of agreement of the two techniques in the clinical context, our findings in phantoms suggest that MPR should be preferred to VRT for the measurement of coronary bifurcation angle by CCTA.
Showing items related by title, author, creator and subject.
Sabarudin, Akmal (2012)Prospective ECG-triggering is regarded as one of the most effective approaches for reduction of radiation dose to patients during coronary CT angiography (CCTA). This study was conducted to investigate the diagnostic ...
An investigation of correlation between left coronary bifurcation angle and hemodynamic changes in coronary stenosis by coronarycomputed tomography angiography-derived computational fluid dynamicsSun, Zhonghua; Chaichana, T. (2017)Background: To investigate the correlation between left coronary bifurcation angle and coronary stenosis as assessed by coronary computed tomography angiography (CCTA)-generated computational fluid dynamics (CFD) analysis ...
Coronary CT angiography in calcified coronary plaques: Comparison of diagnostic accuracy between bifurcation angle measurement and coronary lumen assessment for diagnosing significant coronary stenosis.Sun, Zhonghua; Xu, L.; Fan, Z. (2015)BACKGROUND: To investigate the diagnostic value of coronary CT angiography (CCTA) by bifurcation angle measurement in the assessment of calcified plaques compared to conventional coronary lumen analysis. METHODS: Fifty-three ...