View Item 

Show simple item record

Wnt signalling in gastrointestinal epithelial stem cells

dc.contributor.authorFlanagan, D.
dc.contributor.authorAustin, C.
dc.contributor.authorVincan, Elizabeth
dc.contributor.authorPhesse, T.
dc.date.accessioned2018-05-18T07:56:19Z
dc.date.available2018-05-18T07:56:19Z
dc.date.created2018-05-18T00:23:16Z
dc.date.issued2018
dc.identifier.citationFlanagan, D. and Austin, C. and Vincan, E. and Phesse, T. 2018. Wnt signalling in gastrointestinal epithelial stem cells. Genes. 9 (4): Articel ID 178.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/66837
dc.identifier.doi10.3390/genes9040178
dc.description.abstract

Wnt signalling regulates several cellular functions including proliferation, differentiation, apoptosis and migration, and is critical for embryonic development. Stem cells are defined by their ability for self-renewal and the ability to be able to give rise to differentiated progeny. Consequently, they are essential for the homeostasis of many organs including the gastrointestinal tract. This review will describe the huge advances in our understanding of how stem cell functions in the gastrointestinal tract are regulated by Wnt signalling, including how deregulated Wnt signalling can hijack these functions to transform cells and lead to cancer.
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleWnt signalling in gastrointestinal epithelial stem cells
dc.typeJournal Article
dcterms.source.volume9
dcterms.source.number4
dcterms.source.issn2073-4425
dcterms.source.titleGenes
curtin.departmentSchool of Pharmacy and Biomedical Sciences
curtin.accessStatusOpen access


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

http://creativecommons.org/licenses/by/4.0/
Except where otherwise noted, this item's license is described as http://creativecommons.org/licenses/by/4.0/