Dietary inflammatory index and risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China
MetadataShow full item record
Diet has been shown to have an effect on both inflammation and oesophageal cancer. This study investigated the association between the dietary inflammatory index (DII ® ) and the risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region, China. A case–control study was conducted during 2008–2009 in Urumqi and Shihezi. DII scores were calculated based on dietary intake assessed by a validated FFQ administered to 359 incident oesophageal cancer patients and 380 hospital-based controls. Higher DII scores indicate more pro-inflammatory diets. Logistic regression analyses were performed to assess the association between DII scores and oesophageal cancer risk. Oesophageal cancer patients had a significantly higher median DII score (-0·35; interquartile range (IQR)=-2·25, 1·86) than that of controls (-1·41; IQR -3·07, 0·40). Multivariable logistic analysis revealed a positive association between higher DII scores and oesophageal cancer risk (OR Quartile 4 v. 1 2·55; 95 % CI 1·61, 4·06; P trend < 0·001). A pro-inflammatory diet appears to be associated with an increased risk of oesophageal cancer in Xinjiang Uyghur Autonomous Region. Specific carcinogenic mechanisms are discussed. Accumulating evidence, to which the study contributes, indicates that encouraging the intake of more anti-inflammatory foods may be a strategy to protect against oesophageal cancer in this high-risk area of China.
Showing items related by title, author, creator and subject.
Tang, L.; Lee, Andy; Xu, F.; Zhang, T.; Lei, J.; Binns, Colin (2014)Objective: To ascertain the association between soya consumption, isoflavone intakes and oesophageal cancer risk in remote north-west China, where the incidence of oesophageal cancer is known to be high. Design: Case-control ...
High temperature of food and beverage intake increases the risk of oesophageal cancer in Xinjiang, ChinaTang, L.; Xu, F.; Zhang, T.; Lei, J.; Binns, Colin; Lee, Andy (2013)Background: The north-western region of China has a high incidence of oesophageal cancer. This study aimed to investigate whether the intake of food and beverage at high temperature is associated with the risk of oesophageal ...
Tang, L.; Xu, F.; Zhang, T.; Lei, J.; Binns, Colin; Lee, Andy (2013)Objective: To ascertain the relationship between dietary fibre intake and risk of oesophageal cancer in remote northwest China, where the cancer incidence is known to be high. Methods: A case–control study was conducted ...