The majority of irregular menstrual cycles in adolescence are ovulatory: Results of a prospective study
MetadataShow full item record
Purpose: While ovulation is most likely to occur in adolescent girls with regular menstrual cycles, there are limited data on the incidence of ovulation in girls with irregular menstrual cycles in early postmenarcheal years. The aim of the study was to evaluate the presence of ovulation in healthy postmenarcheal girls with irregular menstrual cycles. Methods, design and subjects: Prospective cohort study over 12 weeks including 40 healthy postmenarcheal girls recruited from the population-based cohort of adolescents from Western Australian Pregnancy Cohort (Raine) Study with irregular menstrual cycles defined by either menstrual cycles <21 days or >35 days in duration or cycle length that varied from month to month by >4 days according to menstrual diaries. Main outcome measure: Ovulation defined by urinary pregnanediol-3α–glucuronide/creatinine measurements higher than three times above minimum value obtained from 12 samples (1 per week). Results: Forty girls (37 Caucasians) with irregular menstrual cycles aged 15.1 (median (IQR) 14.9–15.4) years who were 2.3 (1.9–3.3) years postmenarche were assessed. Urinary pregnanediol-3α–glucuronide/creatinine values identified that 33 girls (82.5%) ovulated during the 3 months of observation and 7 girls had anovulatory cycles. Menstrual diaries collected for a median (IQR) of 159 (137.5–188.2) days showed median minimal and maximum menstrual cycle duration of 24 (11.5–29) and 38.5 (35–48) days, respectively. Conclusions: A large proportion of healthy adolescent girls with irregular menstrual cycles are still ovulating despite irregular and infrequent menses.
Showing items related by title, author, creator and subject.
Clinical, ultrasound and biochemical features of polycystic ovary syndrome in adolescents: Implications for diagnosisHickey, M.; Doherty, D.; Atkinson, Helen; Sloboda, D.; Franks, S.; Norman, R.; Hart, R. (2011)BACKGROUND: Diagnosing polycystic ovary syndrome (PCOS) in adolescence is clinically challenging. The prevalence of clinical, ultrasound and biochemical features of PCOS in a community-based adolescent population using ...
Developing and trialling a school-based ovulatory-menstrual health literacy programme for adolescent girls: A quasi-experimental mixed-method protocolRoux, Felicity; Burns, Sharyn; Chih, Hui Jun; Hendriks, Jacqueline (2019)© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction A review of international and Australian school-based resources ...
Schaumberg, M.; Jenkins, D.; Janse de Jonge, X.; Emmerton, Lynne; Skinner, T. (2016)Objectives: Fluctuating endogenous and exogenous ovarian hormones may influence exercise parameters; yet control and verification of ovarian hormone status is rarely reported and limits current exercise science and sports ...