Determination of the mutagenic potential of commonly marketed Ghanaian medicinal plant formulations using the bacterial reverse mutation assay
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The mutagenic potential of nine commonly marketed Ghanaian medicinal plant aqueous extract formulations determined using the bacterial reverse mutation assay (Ames test) were found to be non-mutagenic. In contrast, one extract, E8 was found to be anti-mutagenic as determined using either a frameshift or a base pair substitution mutant of S. typhimurium in the metabolic activation system. E8 was also found to possess antimicrobial activity against Moraxella catarrhalis.
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