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    Effects of medication, treatment, and behavioral beliefs on intentions to take medication in patients with familial hypercholesterolemia

    Access Status
    Fulltext not available
    Authors
    Hagger, Martin
    Hardcastle, Sarah
    Hu, M.
    Kwok, S.
    Lin, J.
    Nawawi, H.
    Pang, J.
    Santos, R.
    Soran, H.
    Su, T.
    Tomlinson, B.
    Watts, G.
    Date
    2018
    Type
    Journal Article
    
    Metadata
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    Citation
    Hagger, M. and Hardcastle, S. and Hu, M. and Kwok, S. and Lin, J. and Nawawi, H. and Pang, J. et al. 2018. Effects of medication, treatment, and behavioral beliefs on intentions to take medication in patients with familial hypercholesterolemia. Atherosclerosis.
    Source Title
    Atherosclerosis
    DOI
    10.1016/j.atherosclerosis.2018.06.010
    ISSN
    0021-9150
    School
    School of Psychology
    URI
    http://hdl.handle.net/20.500.11937/69626
    Collection
    • Curtin Research Publications
    Abstract

    Background and aims: Although familial hypercholesterolemia (FH) can be effectively managed using cholesterol-lowering medication, patients often fall short of complete treatment adherence. Identifying the psychological factors associated with self-regulation of FH medication is important to inform interventions to maximize adherence. The aim of the present study was to test an integrated psychological model in predicting FH patients' intentions to take medication. Methods: FH patients attending clinics in seven countries were invited to participate in a cross-sectional survey study. Consenting patients (N = 551) completed self-report measures of generalized beliefs about medication overuse and harms, beliefs in treatment effectiveness, specific beliefs about taking medication (attitudes, subjective norms, perceived behavioral control), and intentions to take medication. Participants also completed measures of demographic variables (age, gender, education level, income, cardiovascular disease status). Data were analysed using path analysis controlling for country and demographic variables. Results: Attitudes (ß = .331, p<0.001), subjective norms (ß = .121, p=0.009), and beliefs about medication overuse (ß = -.160, p<0.001) were significant predictors of intentions to take medication. Treatment beliefs predicted intentions indirectly (ß = .088, p<0.001) through attitudes and subjective norms. There was also an indirect effect of beliefs about medication overuse on intentions (ß = -.045, p=0.056), but the effect was small compared with the direct effect. Conclusions: The findings indicate the importance among FH patients of specific beliefs about taking medication and generalized beliefs about medication overuse and treatment in predicting medication intentions. When managing patients, clinicians should emphasize the efficacy of taking cholesterol-lowering drugs and the importance of treatment outcomes, and allay concerns about medication overuse.

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