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dc.contributor.authorSundara Raj, Behin
dc.contributor.supervisorDr Yan Chenen_US
dc.date.accessioned2018-10-25T05:52:53Z
dc.date.available2018-10-25T05:52:53Z
dc.date.issued2018
dc.identifier.urihttp://hdl.handle.net/20.500.11937/70565
dc.description.abstract

This study demonstrated the effects of novel hybrid metal oxide nanoparticles as an effective nano-photosensitizer for the photodynamic therapy against melanoma in vitro and in vivo. A strong synergistic effect was produced by the hybrid NPs and UV-A irradiation. The hybrid nanoparticles modified with folic acid enhanced cellular uptake and exhibited strong anti-tumour activity alone and with UV-A. These hybrid nanoparticles provide us better understanding in designing the semiconductor metal oxides-based nano-photosensitizers for photodynamic therapy.

en_US
dc.publisherCurtin Universityen_US
dc.titlePharmaceutical and Biological Evaluation of Nano Photosensitizers for Cancer Therapyen_US
dc.typeThesisen_US
dcterms.educationLevelPhDen_US
curtin.departmentSchool of Pharmacy and Biomedical Sciencesen_US
curtin.accessStatusOpen accessen_US
curtin.facultyHealth Sciencesen_US


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