Show simple item record

dc.contributor.authorLim, F.
dc.contributor.authorHu, L.
dc.contributor.authorTiekink, E.
dc.contributor.authorDolzhenko, Anton
dc.date.accessioned2018-12-13T09:08:23Z
dc.date.available2018-12-13T09:08:23Z
dc.date.created2018-12-12T02:46:29Z
dc.date.issued2018
dc.identifier.citationLim, F. and Hu, L. and Tiekink, E. and Dolzhenko, A. 2018. One-pot, microwave-assisted synthesis of polymethylene-bridged bis(1H-1,2,4-triazol-5(3)-amines) and their tautomerism. Tetrahedron Letters. 59 (42): pp. 3792-3796.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/70971
dc.identifier.doi10.1016/j.tetlet.2018.09.018
dc.description.abstract

© 2018 Elsevier Ltd A highly selective and efficient method for the synthesis of 3,3'(5,5')-polymethylene-bis(1H-1,2,4-triazol-5(3)-amines) was developed using the reaction of dicarboxylic acids and aminoguanidine in an aqueous medium. This one-pot, microwave-promoted method was proved to be scalable affording the desired products in good yields and purity. The scope of the method was successfully explored by the preparation of a small library of polymethylene-bis(1H-1,2,4-triazol-5(3)-amines) with different alkyl chain linkers. The annular prototropic tautomerism in the prepared compounds was studied using NMR spectroscopy and X-ray crystallography.

dc.publisherPergamon
dc.titleOne-pot, microwave-assisted synthesis of polymethylene-bridged bis(1H-1,2,4-triazol-5(3)-amines) and their tautomerism
dc.typeJournal Article
dcterms.source.volume59
dcterms.source.number42
dcterms.source.startPage3792
dcterms.source.endPage3796
dcterms.source.issn0040-4039
dcterms.source.titleTetrahedron Letters
curtin.departmentSchool of Pharmacy and Biomedical Sciences
curtin.accessStatusFulltext not available


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record