International validation of the EORTC QLQ-PRT20 module for assessment of quality of life symptoms relating to radiation proctitis: a phase IV study
dc.contributor.author | Halkett, Georgia | |
dc.contributor.author | Wigley, C. | |
dc.contributor.author | Aoun, Samar | |
dc.contributor.author | Portaluri, M. | |
dc.contributor.author | Tramacere, F. | |
dc.contributor.author | Livi, L. | |
dc.contributor.author | Detti, B. | |
dc.contributor.author | Arcangeli, S. | |
dc.contributor.author | Lund, J. | |
dc.contributor.author | Kristensen, A. | |
dc.contributor.author | McFadden, N. | |
dc.contributor.author | Grun, A. | |
dc.contributor.author | Bydder, S. | |
dc.contributor.author | Sackerer, I. | |
dc.contributor.author | Greimel, E. | |
dc.contributor.author | Spry, N. | |
dc.contributor.author | EORTC Quality of Life Group | |
dc.date.accessioned | 2018-12-13T09:08:40Z | |
dc.date.available | 2018-12-13T09:08:40Z | |
dc.date.created | 2018-12-12T02:46:25Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Halkett, G. and Wigley, C. and Aoun, S. and Portaluri, M. and Tramacere, F. and Livi, L. and Detti, B. et al. 2018. International validation of the EORTC QLQ-PRT20 module for assessment of quality of life symptoms relating to radiation proctitis: a phase IV study. Radiation Oncology. 13 (1): Article ID 162. | |
dc.identifier.uri | http://hdl.handle.net/20.500.11937/71050 | |
dc.identifier.doi | 10.1186/s13014-018-1107-x | |
dc.description.abstract |
Background: Although patients experience radiation proctitis post radiotherapy no internationally tested instruments exist to measure these symptoms. This Phase IV study tested the scale structure, reliability and validity and cross-cultural applicability of the EORTC proctitis module (QLQ-PRT23) in patients who were receiving pelvic radiotherapy. Methods: Patients (n = 358) from six countries completed the EORTC QLQ-C30, QLQ-PRT23 and EORTC Quality of Life Group debriefing questions. Clinicians completed the EORTC Radiation Therapy Oncology Group scale. Questionnaires were completed at four time-points. The module’s scale structure was examined and validated using standard psychometric analysis techniques. Results: Three items were dropped from the module (QLQ-PRT23 → QLQ-PRT20). Factor analysis identified five factors in the module: bowel control; bloating and gas; emotional function/lifestyle; pain; and leakage. Inter-item correlations were within r = 0.3–0.7. Test-Retest reliability was high. All multi-item scales discriminated between patients showing symptoms and those without symptomology. The module discriminated symptoms from the clinician completed scoring and for age, gender and comorbidities. Conclusion: The EORTC QLQ-PRT20 is designed to be used in addition to the EORTC QLQ-C30 to measure quality of life in patients who receive pelvic radiotherapy. The EORTC QLQ-PRT20 is quick to complete, acceptable to patients, has good content validity and high reliability. Trial registration: Australian and New Zealand Clinical Trials Registry (ANZCTR) ACTRN12609000972224. | |
dc.publisher | BioMed Central | |
dc.relation | https://ro-journal.biomedcentral.com/ | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.title | International validation of the EORTC QLQ-PRT20 module for assessment of quality of life symptoms relating to radiation proctitis: a phase IV study | |
dc.type | Journal Article | |
dcterms.source.volume | 13 | |
dcterms.source.number | 1 | |
dcterms.source.issn | 1748-717X | |
dcterms.source.title | Radiation Oncology | |
curtin.department | School of Nursing, Midwifery and Paramedicine | |
curtin.accessStatus | Open access |