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    Impact of clinical decision support on empirical antibiotic prescribing for children with community-acquired pneumonia

    Access Status
    Fulltext not available
    Authors
    Mostaghim, M.
    Snelling, Thomas
    McMullan, B.
    Ewe, Y.
    Bajorek, B.
    Date
    2018
    Type
    Journal Article
    
    Metadata
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    Citation
    Mostaghim, M. and Snelling, T. and McMullan, B. and Ewe, Y. and Bajorek, B. 2018. Impact of clinical decision support on empirical antibiotic prescribing for children with community-acquired pneumonia. Journal of Pediatrics and Child Health.
    Source Title
    Journal of Pediatrics and Child Health
    DOI
    10.1111/jpc.14191
    ISSN
    1034-4810
    School
    School of Public Health
    URI
    http://hdl.handle.net/20.500.11937/71734
    Collection
    • Curtin Research Publications
    Abstract

    © 2018 Paediatrics and Child Health Division (The Royal Australasian College of Physicians) Aim: To assess the impact of a computerised clinical decision support system (CDSS) on antibiotic use in hospitalised children with a presumptive diagnosis of uncomplicated community-acquired pneumonia (CAP). Methods: Codes associated with lower respiratory tract infection were used to identify cases of presumed uncomplicated CAP requiring admission to a tertiary paediatric hospital. Random sampling of the periods between 1 October 2010 and 30 September 2012 (pre-CDSS) and 1 October 2012 and 30 September 2014 (post-CDSS) determined the sequence of case assessment by two independent investigators. Initial antibiotic therapy, associated CDSS approvals and documented signs of clinical deterioration prior to antibiotic decision-making were recorded. Results: Statistically significant differences between cases pre- and post-CDSS implementation were minimal. High fever was observed in 57.5% (77/134) cases pre-CDSS and 45.8% (49/107) cases post-CDSS (P = 0.07). Supplemental oxygen was used in 30.6% pre-CDSS and 54.2% post-CDSS cases (P < 0.001). Narrow-spectrum penicillins were prescribed most often, with no statistically significant change post-CDSS implementation (81.3% pre-CDSS, 77.6% post-CDSS, P = 0.47). Macrolides were used consistently throughout the study period (53.7% pre-CDSS, 61.7% post-CDSS; P = 0.21). Conclusion: CDSS implementation did not reduce already low rates of broad-spectrum antibiotic use for uncomplicated CAP.

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