Show simple item record

dc.contributor.authorPontier, J.
dc.contributor.authorBuzzacott, Peter
dc.contributor.authorNastorg, J.
dc.contributor.authorDinh-Xuan, A.
dc.contributor.authorLambrechts, K.
dc.identifier.citationPontier, J. and Buzzacott, P. and Nastorg, J. and Dinh-Xuan, A. and Lambrechts, K. 2014. Exhaled nitric oxide concentration and decompression-induced bubble formation: An index of decompression severity in humans?. Nitric Oxide: Biology and Chemistry. 39 (1): pp. 29-34.

Introduction Previous studies have highlighted a decreased exhaled nitric oxide concentration (FE NO) in divers after hyperbaric exposure in a dry chamber or following a wet dive. The underlying mechanisms of this decrease remain however unknown. The aim of this study was to quantify the separate effects of submersion, hyperbaric hyperoxia exposure and decompression-induced bubble formation on FE NO after a wet dive. Methods Healthy experienced divers (n = 31) were assigned to either (i) a group making a scuba-air dive (Air dive), (ii) a group with a shallow oxygen dive protocol (Oxygen dive) or (iii) a group making a deep dive breathing a trimix gas mixture (deep-dive). Bubble signals were graded with the KISS score. Before and after each dive FE NO values were measured using a hand-held electrochemical analyzer. Results There was no change in post-dive values of FE NO values (expressed in ppb = parts per billion) in the Air dive group (15.1 ± 3.6 ppb vs. 14.3 ± 4.7 ppb, n = 9, p = 0.32). There was a significant decrease in post-dive values of FE NO in the Oxygen dive group (15.6 ± 6 ppb vs. 11.7 ± 4.7 ppb, n = 9, p = 0.009). There was an even more pronounced decrease in the deep dive group (16.4 ± 6.6 ppb vs. 9.4 ± 3.5 ppb, n = 13, p < 0.001) and a significant correlation between KISS bubble score >0 (n = 13) and percentage decrease in post-dive FE NO values (r = -0.53, p = 0.03). Discussion Submersion and hyperbaric hyperoxia exposure cannot account entirely for these results suggesting the possibility that, in combination, one effect magnifies the other. A main finding of the present study is a significant relationship between reduction in exhaled NO concentration and dive-induced bubble formation. We postulate that exhaled NO concentration could be a useful index of decompression severity in healthy human divers. © 2014 Published by Elsevier Inc.

dc.publisherElsevier Inc
dc.titleExhaled nitric oxide concentration and decompression-induced bubble formation: An index of decompression severity in humans?
dc.typeJournal Article
dcterms.source.titleNitric Oxide: Biology and Chemistry
curtin.departmentSchool of Nursing, Midwifery and Paramedicine
curtin.accessStatusFulltext not available

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record