Show simple item record

dc.contributor.authorYong, Y.
dc.contributor.authorDykes, Gary
dc.contributor.authorLee, S.
dc.contributor.authorChoo, W.
dc.date.accessioned2018-12-13T09:12:53Z
dc.date.available2018-12-13T09:12:53Z
dc.date.created2018-12-12T02:46:30Z
dc.date.issued2018
dc.identifier.citationYong, Y. and Dykes, G. and Lee, S. and Choo, W. 2018. Biofilm inhibiting activity of betacyanins from red pitahaya (Hylocereus polyrhizus) and red spinach (Amaranthus dubius) against Staphylococcus aureus and Pseudomonas aeruginosa biofilms. Journal of Applied Microbiology.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/72252
dc.identifier.doi10.1111/jam.14091
dc.description.abstract

© 2018 The Society for Applied Microbiology Aims: To investigate the biofilm inhibitory activity of betacyanins from red pitahaya (Hylocereus polyrhizus) and red spinach (Amaranthus dubius) against Staphylococcus aureus and Pseudomonas aeruginosa biofilms. Methods and Results: The pulp of red pitahaya and the leaves of red spinach were extracted using methanol followed by subfractionation to obtain betacyanin fraction. The anti-biofilm activity was examined using broth microdilution assay on polystyrene surfaces and expressed as minimum biofilm inhibitory concentration (MBIC). The betacyanin fraction from red spinach showed better anti-biofilm activity (MBIC: 0·313–1·25 mg ml-1) against five Staph. aureus strains while the betacyanin fraction from red pitahaya showed better anti-biofilm activity (MBIC: 0·313–0·625 mg ml-1) against four P. aeruginosa strains. Both betacyanin fraction significantly reduced hydrophobicity of Staph. aureus and P. aeruginosa strains. Numbers of Staph. aureus and P. aeruginosa attached to polystyrene were also reduced without affecting their cell viability. Conclusion: Betacyanins can act as anti-biofilm agents against the initial step of biofilm formation, particularly on a hydrophobic surface like polystyrene. Significance and Impact of the Study: This study is the first to investigate the use of betacyanin as a biofilm inhibitory agent. Betacyanin could potentially be used to reduce the risk of biofilm-associated infections.

dc.publisherBlackwell Science Ltd
dc.titleBiofilm inhibiting activity of betacyanins from red pitahaya (Hylocereus polyrhizus) and red spinach (Amaranthus dubius) against Staphylococcus aureus and Pseudomonas aeruginosa biofilms
dc.typeJournal Article
dcterms.source.issn1364-5072
dcterms.source.titleJournal of Applied Microbiology
curtin.departmentSchool of Public Health
curtin.accessStatusFulltext not available


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record