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    Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis

    Access Status
    Fulltext not available
    Authors
    Di Mattia, F.
    Fary, Robyn
    Murray, K.
    Howie, E.
    Smith, Anne
    Morris, Susan
    Date
    2018
    Type
    Journal Article
    
    Metadata
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    Citation
    Di Mattia, F. and Fary, R. and Murray, K. and Howie, E. and Smith, A. and Morris, S. 2018. Two subtypes of symptomatic joint hypermobility: A descriptive study using latent class analysis. Archives of Disease in Childhood.
    Source Title
    Archives of Disease in Childhood
    DOI
    10.1136/archdischild-2017-314149
    ISSN
    0003-9888
    School
    School of Physiotherapy and Exercise Science
    URI
    http://hdl.handle.net/20.500.11937/72276
    Collection
    • Curtin Research Publications
    Abstract

    Objective: To investigate a cohort of children with symptomatic joint hypermobility. Methods: Case notes for 318 children with joint hypermobility attending a rheumatology clinic were reviewed for clinical presentation, medical history, psychosocial factors and physical examination findings. Seven key variables were extracted and used as indicator variables in a latent class analysis to estimate the presence and number of subgroups of children with symptomatic joint hypermobility. Results: Two subgroups with differing clinical presentations were identified accounting for age and gender: an 'athletic-persistent' class (62%) characterised by higher probabilities for recurrent and chronic musculoskeletal pain, and less severe hypermobility; and a 'systemic-profound' class (38%) characterised by generalised hypermobility, recurrent musculoskeletal pain, gastro-oesophageal reflux and motor delay. Conclusion: Findings suggest the presence of two distinct presentations of children with hypermobility. This finding may be important for clinical decision-making and management of this group of children.

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