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    Age, weight and decompression sickness in rats

    Access Status
    Fulltext not available
    Authors
    Buzzacott, Peter
    Theron, M.
    Mazur, A.
    Wang, Q.
    Lambrechts, K.
    Eftedal, I.
    Ardestani, S.
    Guerrero, F.
    Date
    2016
    Type
    Journal Article
    
    Metadata
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    Citation
    Buzzacott, P. and Theron, M. and Mazur, A. and Wang, Q. and Lambrechts, K. and Eftedal, I. and Ardestani, S. et al. 2016. Age, weight and decompression sickness in rats. Archives of Physiology and Biochemistry. 122 (2): pp. 67-69.
    Source Title
    Archives of Physiology and Biochemistry
    DOI
    10.3109/13813455.2016.1140787
    ISSN
    1381-3455
    School
    School of Nursing, Midwifery and Paramedicine
    URI
    http://hdl.handle.net/20.500.11937/72585
    Collection
    • Curtin Research Publications
    Abstract

    © 2015 Taylor and Francis. Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference between DCS outcome at ages 11 or 13 weeks in matched rats (p = 0.002). Discussion: Even with weight included in the model, age was significantly associated with DCS (p = 0.01), yet after removal of weight the association was much stronger (p = 0.002). Conclusion: We believe that age is likely to be found associated with the probability of DCS in a larger dataset with a wider range of parameters, after accounting for the effect of weight.

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