A rat model of chronic moderate alcohol consumption and risk of decompression sickness
MetadataShow full item record
© 2015, South Pacific Underwater Medicine Society. All rights reserved. Introduction: This study aimed to establish if chronic, moderate, pre-dive alcohol consumption had any affect upon susceptibility to decompression sickness (DCS) in rats. Methods: A treatment group of 15 rats were given water containing 12 mL·L-1 of ethanol for four weeks. Controls (n = 15) were given water. Both groups were compressed with air to 1,000 kPa, followed by staged decompression. An additional 30 control rats from a similar previous experiment were added, raising the control-treatment ratio to 3:1. Results: Rats in the treatment group consumed the equivalent of an 80 kg man drinking 2 L of 5% alcohol by volume beer per day, which is three times the recommended daily limit for men. Overall, comparing the treatment group with the combined control groups neither weight (P = 0.23) nor alcohol consumption (P = 0.69) were associated with DCS. Discussion: We observed that chronic, moderate alcohol consumption prior to compression was neither prophylactic nor deleterious for DCS in young, male rats.
Showing items related by title, author, creator and subject.
The impact of lifestyle factors on the clinical outcomes of in vitro fertilisation-embryo transfer (IVF) treatmentJoesbury, Karen Ann (2003)Objectives: To determine the effect of female and male cigarette smoking, caffeine and alcohol consumption, stress and indicators of dietary status on the clinical outcomes of NF treatment. Design: Prospective cohort ...
Alcohol-related biases in selective attention and action tendency make distinct contributions to dysregulated drinking behaviourSharbanee, Jason; Stritzke, W.; Wiers, R.; Macleod, C. (2013)Aims: To assess whether alcohol-related biases in selective-attention and action tendency uniquely or concurrently predict the ability to regulate alcohol consumption. Design and participants: Two groups of undergraduate ...
Stockwell, Tim; Chikritzhs, Tanya; Hendrie, Delia; Fordham, R.; Ying, F.; Phillips, M.; Cronin, J.; O'Reilly, B. (2001)An evaluation is presented of the impact of a comprehensive population-based alcohol harmreduction programme in the Northern Territory funded by a levy of 5 cents per standard drink which took effect from April 1992. The ...