In vitro investigation of bioactivities of solid-state fermented lupin, quinoa and wheat using Lactobacillus spp.
MetadataShow full item record
This study is an in-vitro investigation of the health-promoting properties of fermented whole-grain lupin, quinoa and wheat, using 72 h solid-state fermentation by Lactobacillus reuteri K777 and Lb. plantarum K779. Antiproliferative activity against Caco-2 and MCF-7 cancer cell lines (tumour cell lines of intestinal and mammary origin, respectively) was investigated, as well as a-amylase and a-glucosidase inhibition, antihypertensive, antioxidant and proteolytic activities. ABTS antioxidant activities of fermented lupin (FL, 55% w/v), quinoa (FQ, 55% w/v) and wheat (FW, 55% w/v) ranged from ~12.0% to 55.0%, ~17.6% to 73.0%, and ~29.0% to 26.0%, respectively. Lupin, quinoa and wheat fermented by L. plantarum had pronounced antihypertensive activities (~85%). The a-glucosidase inhibition in FL was higher than that of FQ and FW. The magnitude of the antiproliferative activities of FL was markedly greater (p < 0.05) than of FQ and FW by approximately three-fold and two-folds against Caco-2 and MCF-7 cell lines, respectively.
Showing items related by title, author, creator and subject.
Cytotoxicity, antihypertensive, antidiabetic and antioxidant activities of solid-state fermented lupin, quinoa and wheat by Bifidobacterium species: In-vitro investigationsAyyash, M.; Johnson, Stuart; Liu, S.; Al-Mheiri, A.; Abushelaibi, A. (2018)© 2018 Elsevier Ltd This study aimed to investigate the in-vitro cytotoxicity activity against two cancer cell lines, a-amylase and a-glucosidase inhibitions, ACE-inhibition, antioxidant and proteolytic activities of ...
Growth, enzymatic glutathione peroxidase activity and biochemical status of juvenile barramundi (Lates calcarifer) fed dietary fermented lupin meal supplemented with organic seleniumIlham, I.; Hapsari, F.; Fotedar, Ravi (2018)© 2017 John Wiley & Sons Ltd To investigate the effects of high level of lupin meal (LM) supplemented with organic selenium (OS) on the growth and blood biochemistry of barramundi (Lates calcarifer), four isocaloric and ...
Development of a fermented product with higher phenolic compounds and lower anti-nutritional factors from germinated lupin (Lupinus angustifolius L.)Khan, M.; Karnpanit, W.; Nasar-Abbas, S.; Huma, Z.; Jayasena, Vijay (2018)© 2018 Wiley Periodicals, Inc. The nutritional profile of lupin (Lupinus angustifolius L.) seeds has recently increased the scientific importance to develop variety of lupin-enriched food products. In this study, a fermented ...