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dc.contributor.authorBetts, K.
dc.contributor.authorChan, G.
dc.contributor.authorMcIlwraith, F.
dc.contributor.authorDietze, P.
dc.contributor.authorWhittaker, E.
dc.contributor.authorBurns, L.
dc.contributor.authorAlati, Rosa
dc.date.accessioned2018-12-13T09:15:44Z
dc.date.available2018-12-13T09:15:44Z
dc.date.created2018-12-12T02:47:13Z
dc.date.issued2016
dc.identifier.citationBetts, K. and Chan, G. and McIlwraith, F. and Dietze, P. and Whittaker, E. and Burns, L. and Alati, R. 2016. Differences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies. Addiction. 111 (7): pp. 1214-1223.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/73175
dc.identifier.doi10.1111/add.13339
dc.description.abstract

© 2016 Society for the Study of Addiction Aims: To test if polysubstance use profiles and drug-related outcomes differ between those receiving and not receiving opioid substitution therapies (OST) among people who inject drugs (PWID). Design: An annual cross-sectional, sentinel sample of PWID across Australia. Setting: Data came from 3 years (2011–13) of the Illicit Drug Reporting System (IDRS). Participants: A total of 2673 participants who injected drugs from the combined national IDRS samples of 2011 (n = 868), 2012 (n = 922) and 2013 (n = 883). Measurements: Latent class analysis (LCA) was used to summarize participants' self-reported use of 18 types of substances, with the resulting polysubstance use profiles then associated with participant experience of a number of drug-related outcomes. Findings: Polysubstance use profiles exhibiting a broad range of substance use were generally at increased risk of negative drug-related outcomes, whether or not participants were receiving OST, including thrombosis among OST receivers [odds ratio (OR) = 2.13, 95% confidence intervals (CI) = 1.09–4.17], injecting with used needles among OST receivers and non-receivers, respectively (OR = 2.78, 95% CI = 1.50–5.13; OR = 2.15, 95% CI = 1.34–3.45) and violent criminal offences among OST receivers and non-receivers, respectively (OR =2.30, 95% CI = 1.16–4.58; OR = 1.87, 95% CI = 1.14–3.07). An important exception was non-fatal overdose which was related specifically to a class of PWID who were not receiving OST and used morphine frequently (OR = 1.83, 95% CI = 1.06–3.17). Conclusion: Regardless of opioid substitution therapies usage, people who inject drugs who use a broad-range of substances experience greater levels of injecting-related injuries and poorer health outcomes and are more likely to engage in criminal activity than other groups of people who inject drugs.

dc.publisherWiley-Blackwell Publishing Ltd.
dc.titleDifferences in polysubstance use patterns and drug-related outcomes between people who inject drugs receiving and not receiving opioid substitution therapies
dc.typeJournal Article
dcterms.source.volume111
dcterms.source.number7
dcterms.source.startPage1214
dcterms.source.endPage1223
dcterms.source.issn0965-2140
dcterms.source.titleAddiction
curtin.departmentSchool of Public Health
curtin.accessStatusFulltext not available


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