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    Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions

    Access Status
    Fulltext not available
    Authors
    Cox, D.
    Khoo, S.
    Zhang, Guicheng
    Lindsay, K.
    Keil, A.
    Knight, G.
    Gern, J.
    Laing, I.
    Bizzintino, J.
    Le Souëf, P.
    Date
    2018
    Type
    Journal Article
    
    Metadata
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    Citation
    Cox, D. and Khoo, S. and Zhang, G. and Lindsay, K. and Keil, A. and Knight, G. and Gern, J. et al. 2018. Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions. European Respiratory Journal. 52 (2).
    Source Title
    European Respiratory Journal
    DOI
    10.1183/13993003.00207-2018
    ISSN
    0903-1936
    School
    School of Public Health
    URI
    http://hdl.handle.net/20.500.11937/73285
    Collection
    • Curtin Research Publications
    Abstract

    Respiratory virus infections account for a significant proportion of acute admissions to the paediatric intensive care unit (PICU). Recent studies have shown that rhinoviruses (RV) are the most frequent virus detected in severe cases of acute respiratory illnesses (ARI) admitted to a PICU. The aim of this study was to determine the prevalence of different viruses, in particular RV species, in children with ARI admitted to a tertiary PICU. Nasopharyngeal aspirates (NPA) from 229 children admitted to PICU with an ARI were analysed. RV was the most common virus detected, being present in 94 (41.0%) of samples examined, followed by respiratory syncytial virus (RSV) which was identified in 50 (21.8%) samples. A subsection analysis of cases with residual sample available of sufficient quality to allow for RV species typing showed that overall, the percentage of PICU admissions for each RV species was 22.3% for RV-C, 17.5% for RV-A and 1.7% for RV-B. This study demonstrated that RV is the most frequent virus identified in children admitted to a tertiary PICU with an ARI and RV-C is the most common RV species detected. Importantly, in the children admitted to PICU with an ARI, RV-C was by itself as common a pathogen as RSV.

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