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dc.contributor.authorYee, Yan Jing
dc.contributor.supervisorYan Chenen_US
dc.date.accessioned2019-02-25T06:53:39Z
dc.date.available2019-02-25T06:53:39Z
dc.date.issued2018en_US
dc.identifier.urihttp://hdl.handle.net/20.500.11937/73581
dc.description.abstract

Resveratrol is known to undergo rapid metabolism and degradation in vivo. The aim of this project is to synthesise polymeric resveratrol conjugates for formulation into nanoparticles for enhanced anticancer treatment by decreasing the metabolism and degradation rate of resveratrol in vivo. Conjugated resveratrol nanoparticles were found to suppress tumour growth in vivo in a melanoma mouse model although in vitro data shows lesser anti-proliferative effect than resveratrol alone.

en_US
dc.publisherCurtin Universityen_US
dc.titleEvaluation of Novel Resveratrol Conjugate and Nanoparticle Formulations for Enhanced Anticancer Activityen_US
dc.typeThesisen_US
dcterms.educationLevelPhDen_US
curtin.departmentSchool of Pharmacy and Biomedical Sciencesen_US
curtin.departmentCurtin Health Innovation Research Instituteen_US
curtin.accessStatusOpen accessen_US
curtin.facultyHealth Sciencesen_US


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