Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization
|dc.identifier.citation||Elbez, Y. and Cheong, A. and Fassa, A. and Cohen, E. and Reid, C. and Babarskiene, R. and Bhatt, D. et al. 2016. Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization. European Heart Journal - Quality of Care and Clinical Outcomes. 2 (1): pp. 23-32.|
Aims: The aim was to describe outcomes among patients with stable coronary artery disease (CAD) with or without a history of myocardial revascularization in a large contemporary cohort. Methods and results: Patients with stable CAD were selected from the Reduction of Atherothrombosis for Continued Health (REACH) registry. The cohort was divided into patients with (n = 25 583) and without (n = 13 133) a history of myocardial revascularization. Crude outcomes were described according to the use and type of revascularization: percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG). The primary outcome was cardiovascular (CV) death. At baseline, the non-revascularized group was older and had more CV risk factors. At 36-month median followup, previous revascularization was associated with a lower risk of CV death [crude incidence rate (CIR): 6.82 vs. 9.08%, hazard ratio (HR) 0.73 [95% confidence interval (CI) 0.66.0.80]; P < 0.01]. This association was seen for patients with a history of PCI (CIR 5.78 vs. 8.88%, HR 0.64 [0.58.0.71]; P = 0.01), but not with CABG (HR 1.26 [184.108.40.206]; P < 0.01), and was consistent regardless of prior MI and the timing of prior revascularization. Conclusion: Among patients with stable CAD, a history of myocardial revascularization was associated with lower CV mortality, particularly when PCI was the mode of revascularization. Coronary artery disease patients managed non-invasively represent a high-risk group.
|dc.title||Clinical outcomes in patients with stable coronary artery disease with vs. without a history of myocardial revascularization|
|dcterms.source.title||European Heart Journal - Quality of Care and Clinical Outcomes|
|curtin.department||School of Public Health|
|curtin.accessStatus||Fulltext not available|
Files in this item
There are no files associated with this item.