Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Night-time ambulatory blood pressure is the best pretreatment blood pressure predictor of 11-year mortality in treated older hypertensives

    Access Status
    Fulltext not available
    Authors
    Wing, L.
    Chowdhury, E.
    Reid, Christopher
    Beilin, L.
    Brown, M.
    Date
    2018
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Wing, L. and Chowdhury, E. and Reid, C. and Beilin, L. and Brown, M. 2018. Night-time ambulatory blood pressure is the best pretreatment blood pressure predictor of 11-year mortality in treated older hypertensives. Blood Pressure Monitoring. 23 (5): pp. 237-243.
    Source Title
    Blood Pressure Monitoring
    DOI
    10.1097/MBP.0000000000000331
    ISSN
    1359-5237
    School
    School of Public Health
    URI
    http://hdl.handle.net/20.500.11937/74554
    Collection
    • Curtin Research Publications
    Abstract

    Background: Numerous studies have shown a stronger relationship between ambulatory blood pressure (ABP), particularly night ABP, and cardiovascular events/mortality than for office blood pressure (OBP). A previous clinical trial (Syst-Eur) showed that pretreatment ABP was only a better predictor of outcome than OBP in placebo-treated participants. The current study in treated elderly hypertensives from the Second Australian National Blood Pressure study (ANBP2) examined whether pretreatment ABP was a better predictor of mortality than OBP over long-term (~11 years) follow-up. Participants and methods: ANBP2 was a comparative outcome trial in 6083 off-treatment or previously untreated elderly hypertensives. In the ABP substudy, at study entry, participants had ABP and nurse-performed OBP measurements. Cox proportional hazards analysis assessed the relationships between both OBP and ABP at study entry and 11-year all-cause and cardiovascular mortality, with results pooled from both active treatment phases. Results: In 702 participants, over a median of 10.8 years, including 6.7 years after the trial, 167 died (82 cardiovascular). Pretreatment 'night' systolic ABP and pulse pressure were the best predictors of '11-year' cardiovascular mortality (hazard ratios: 1.26; 95% confidence intervals: 1.10-1.45, P=0.001 and 1.18; 1.06-1.31, P=0.003, respectively) and all-cause mortality (hazard ratios: 1.15; 95% confidence intervals:1.05-1.28, P=0.005 and 1.09; 1.10-1.31, P=0.03, respectively). OBP was not a significant predictor of mortality. Conclusion: In actively treated elderly hypertensives participating in ANBP2, all-cause or cardiovascular deaths were significantly related to pretreatment ABP, particularly to night-time systolic ABP and pulse pressure, but not to OBP.

    Related items

    Showing items related by title, author, creator and subject.

    • Visit-to-visit (long-term) and ambulatory (short-term) blood pressure variability to predict mortality in an elderly hypertensive population
      Chowdhury, Enayet; Wing, L.; Jennings, G.; Beilin, L.; Reid, Christopher (2018)
      © Copyright 2018 Wolters Kluwer Health, Inc. All rights reserved. Objectives: To explore the association of different types of blood pressure (BP) variability measures estimated from either short-term ambulatory ...
    • Association of depression with mortality in an elderly treated hypertensive population
      Chowdhury, E.; Berk, M.; Nelson, M.; Wing, L.; Reid, Christopher (2018)
      Background:Both elevated blood pressure and/or depression increase the risk of cardiovascular disease and mortality. This study in treated elderly hypertensive patients explored the incidence of depression, its association ...
    • Change in Blood Pressure Variability Among Treated Elderly Hypertensive Patients and Its Association With Mortality
      Chowdhury, Enayet ; Nelson, M.R.; Wing, L.M.H.; Jennings, G.L.R.; Beilin, L.J.; Reid, Christopher ; Bruce, A.; Beckinsale, P.; Thompson, J.; McMurchie, M.; Fraser, G.; Gleave, D.; Cope, V.; DeLooze, F.; Moore, S.; Dibben, C.; Newbury, J.; McDermott, B.; Willson, K.; Bear, C.; Harrap, S.; Johnston, C.; Ryan, P.; Brown, M.; Ryan, P.; Fletcher, P.; Feneley, M.; Dewar, E.; Marley, J.; Marley, J.; Moss, J.; Webb, P.; Glasziou, P.; Boyle, F.; Primrose, J.; Piterman, L.; De Looze, F.; Dickinson, J.; Gambrill, J.; Joseph, P.; Donnan, G.; Morgan, T.; Whitworth, J.; MacMahon, S.; Silagy, C. (2019)
      Background: Information is scarce regarding effects of antihypertensive medication on blood pressure variability (BPV) and associated clinical outcomes. We examined whether antihypertensive treatment changes BPV over time ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.