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dc.contributor.authorBeh, Jane
dc.contributor.authorFarah, S.
dc.contributor.authorLanger, R.
dc.contributor.authorJaklenec, A.
dc.contributor.editorDomb, A.
dc.contributor.editorKunduru, K.
dc.contributor.editorFarah, S.
dc.date.accessioned2019-09-17T03:46:51Z
dc.date.available2019-09-17T03:46:51Z
dc.date.issued2019
dc.identifier.urihttp://hdl.handle.net/20.500.11937/76318
dc.identifier.doi10.1039/9781788012638-00325
dc.description.abstract

Biopolymers have been found useful in biomedical applications because of their biocompatibility and degradability in the human body. Biopolymers can be formed naturally in living organisms and include polypeptides from proteins, polysaccharides from polymeric carbohydrates and polynucleotides from nucleic acids – deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). Biopolymers can also be synthesized by using natural biological materials such as starch, sugars, fats, cellulose, and oils.

Unsterilized biopolymers can cause severe infections in the human body when they are used for biomedical applications. Hence, biopolymers are required to undergo sterilization, which is a process to inactivate microorganisms including bacteria, spores, fungus, and viruses. The biopolymers that have been sterilized include both the natural and synthetic biodegradable polymers such as chitosan, hyaluronic acid, polylactic acid, poly-L-lactic acid, and poly(lactide-co-glycolide), are being reviewed in this paper. Various sterilization methods that have been applied on biopolymers include steam-autoclaving, dry heat sterilization, irradiation (gamma, X-rays, ultraviolet, and electron beam), chemical treatment (ethylene oxide), gas plasma, and supercritical fluid sterilization, are reviewed.

dc.publisherRoyal Society of Chemistry
dc.titleMethods for Sterilization of Biopolymers for Biomedical Applications
dc.typeBook Chapter
dcterms.source.startPage325
dcterms.source.endPage347
dcterms.source.titleAntimicrobial Materials for Biomedical Applications
dcterms.source.seriesBiomaterials Science
dcterms.source.isbn978-1-78801-188-4
dcterms.source.placeUnited Kingdom
dcterms.source.chapter12
dc.date.updated2019-09-17T03:46:51Z
curtin.accessStatusFulltext not available
curtin.contributor.orcidBeh, Jane [0000-0002-5563-8795]
curtin.contributor.scopusauthoridBeh, Jane [55033508000]


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