Homochirality in biomineral suprastructures induced by assembly of single-enantiomer amino acids from a nonracemic mixture
MetadataShow full item record
© 2019, The Author(s). Since Pasteur first successfully separated right-handed and left-handed tartrate crystals in 1848, the understanding of how homochirality is achieved from enantiomeric mixtures has long been incomplete. Here, we report on a chirality dominance effect where organized, three-dimensional homochiral suprastructures of the biomineral calcium carbonate (vaterite) can be induced from a mixed nonracemic amino acid system. Right-handed (counterclockwise) homochiral vaterite helicoids are induced when the amino acid l-Asp is in the majority, whereas left-handed (clockwise) homochiral morphology is induced when d-Asp is in the majority. Unexpectedly, the Asp that incorporates into the homochiral vaterite helicoids maintains the same enantiomer ratio as that of the initial growth solution, thus showing chirality transfer without chirality amplification. Changes in the degree of chirality of the vaterite helicoids are postulated to result from the extent of majority enantiomer assembly on the mineral surface. These mechanistic insights potentially have major implications for high-level advanced materials synthesis.
Showing items related by title, author, creator and subject.
A configurational and conformational study of aframodial and its diasteriomers via experimental and theoretical VA and VCD spectroscopiesJalkanen, Karl; Gale, Julian (2007)In thiswork we present the experimental and theoretical vibrational absorption (VA) and the theoretical vibrational circular dichroism (VCD) spectra for aframodial. In addition, we present the theoretical VA and VCD spectra ...
Demichelis, Raffaella; Raiteri, Paolo; Gale, Julian (2013)The structures of both ikaite (CaCO3·6H2O) and monohydrocalcite (CaCO3·H2O) were computed at the PBE0 level of theory, using all electron Gaussian type basis sets. Correction for the long-range dispersion contribution was ...
Demichelis, Raffaella; Raiteri, Paolo; Gale, Julian; Dovesi, Roberto (2013)For many years the nature of the disordered structure of vaterite, a calcium carbonate polymorph that plays a significant role in biomineralisation, has been debated. In the past year, two independent studies (Angew. ...