Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Theses
    • View Item
    • espace Home
    • espace
    • Curtin Theses
    • View Item

    The role of genetic diversity in the replication, pathogenicity and virulence of Murray Valley encephalitis virus

    225949_Niazi 2014.pdf (4.663Mb)
    Access Status
    Open access
    Authors
    Niazi, Aziz-ur-Rahman
    Date
    2013
    Supervisor
    Assoc. Prof. Cheryl Johansen
    Dr Beng Hooi Chua
    Dr Paul Costantino
    Dr David Thomas Williams
    Prof. Ricardo Mancera
    Type
    Thesis
    Award
    PhD
    
    Metadata
    Show full item record
    School
    School of Biomedical Sciences
    URI
    http://hdl.handle.net/20.500.11937/774
    Collection
    • Curtin Theses
    Abstract

    Genetic and phenotypic variation of genotype 1 (G1) and genotype 2 (G2) Murray valley encephalitis virus (MVEV) were characterised. G2 viruses were a minority, had lower levels of genetic diversity and an attenuated phenotype in the mouse model of MVE. G1 isolates were abundant with higher levels of genetic diversity and a virulent phenotype. The restricted evolution of MVEV was due to multiplication in mosquito cells. An RT-qPCR assay detecting all MVEV genotypes was developed.

    Related items

    Showing items related by title, author, creator and subject.

    • Secondary students' understanding of the gene concept : an analysis of conceptual change from multiple perspectives.
      Venville, Grady J. (1997)
      A journey into the past century of genetics history reveals transformations of the concept of the gene through notions of discrete units that obeyed Mendelian laws to the modem bewildering gene concept. We can no longer ...
    • Australian twin and molecular genetic study on attention deficit hyperactivity disorder and its co-morbidity with reading disability
      Sheikhi, Abdullah (2008)
      Aim: This study aims to investigate the genetic components of Attention Deficit Hyperactivity Disorder (ADHD), Reading Disability (RD), and their comorbidity. Methods: Three approaches were applied to data from 2610 ...
    • Genetic connectivity and inter-population seed dispersal of Banksia hookeriana at the landscape scale
      He, Tianhua; Lamont, Byron; Krauss, S.; Enright, Neal (2010)
      Background and Aims: Landscape genetics combines approaches from population genetics and landscape ecology, increasing the scope for conceptual advances in biology. Banksia hookeriana comprises clusters of individuals ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.