Investigation of Novel Biomarkers for Pancreatic Cancer
| dc.contributor.author | Emmanouilidi, Aikaterini | |
| dc.contributor.supervisor | Marco Falasca | en_US |
| dc.contributor.supervisor | Pat Metharom | en_US |
| dc.date.accessioned | 2020-03-19T05:30:41Z | |
| dc.date.available | 2020-03-19T05:30:41Z | |
| dc.date.issued | 2019 | en_US |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/78328 | |
| dc.description.abstract |
Pancreatic ductal adenocarcinoma (PDAC) is a disease with dismal prognosis and an 8% chance of survival 5 years post-diagnosis, and is very challenging diagnostically and therapeutically. Exosomes are nanometre-sized vesicles known to mediate cancer spread and chemotherapy resistance. In this study, a comprehensive proteomic and lipidomic analysis of PDAC-derived exosomes has been performed. A specific enrichment of key signalling proteins and lipids with a potential role in PDAC progression has been identified. | en_US |
| dc.publisher | Curtin University | en_US |
| dc.title | Investigation of Novel Biomarkers for Pancreatic Cancer | en_US |
| dc.type | Thesis | en_US |
| dcterms.educationLevel | PhD | en_US |
| curtin.department | School of Pharmacy and Biomedical Sciences | en_US |
| curtin.accessStatus | Open access | en_US |
| curtin.faculty | Health Sciences | en_US |