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dc.contributor.authorEmmanouilidi, Aikaterini
dc.contributor.supervisorMarco Falascaen_US
dc.contributor.supervisorPat Metharomen_US
dc.date.accessioned2020-03-19T05:30:41Z
dc.date.available2020-03-19T05:30:41Z
dc.date.issued2019en_US
dc.identifier.urihttp://hdl.handle.net/20.500.11937/78328
dc.description.abstract

Pancreatic ductal adenocarcinoma (PDAC) is a disease with dismal prognosis and an 8% chance of survival 5 years post-diagnosis, and is very challenging diagnostically and therapeutically. Exosomes are nanometre-sized vesicles known to mediate cancer spread and chemotherapy resistance. In this study, a comprehensive proteomic and lipidomic analysis of PDAC-derived exosomes has been performed. A specific enrichment of key signalling proteins and lipids with a potential role in PDAC progression has been identified.

en_US
dc.publisherCurtin Universityen_US
dc.titleInvestigation of Novel Biomarkers for Pancreatic Canceren_US
dc.typeThesisen_US
dcterms.educationLevelPhDen_US
curtin.departmentSchool of Pharmacy and Biomedical Sciencesen_US
curtin.accessStatusOpen accessen_US
curtin.facultyHealth Sciencesen_US


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