Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    The Causal Role of the Dorsolateral Prefrontal Cortex in the Modification of Attentional Bias: Evidence from Transcranial Direct Current Stimulation

    Access Status
    Fulltext not available
    Authors
    Clarke, Patrick
    Browning, M.
    Hammond, G.
    Notebaert, L.
    MacLeod, C.
    Date
    2014
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Clarke, P. and Browning, M. and Hammond, G. and Notebaert, L. and MacLeod, C. 2014. The Causal Role of the Dorsolateral Prefrontal Cortex in the Modification of Attentional Bias: Evidence from Transcranial Direct Current Stimulation. Biological Psychiatry. 76 (12): pp. 946-952.
    Source Title
    Biological Psychiatry
    DOI
    10.1016/j.biopsych.2014.03.003
    ISSN
    1873-2402
    School
    School of Psychology and Speech Pathology
    URI
    http://hdl.handle.net/20.500.11937/7946
    Collection
    • Curtin Research Publications
    Abstract

    Background: A pattern of attentional bias for threatening information is thought to be involved in the etiology of anxiety. Consistent with this idea, cognitive training techniques directly targeting such patterns of biased attention have been shown to reduce symptoms of anxiety. Research seeking to establish the neurologic underpinnings of change in the attentional bias for threat have implicated, but not confirmed, the role of lateral prefrontal regions. Methods: The current study sought to confirm experimentally the causal role of lateral prefrontal areas in the modification of attentional bias by delivering targeted cortical stimulation during attention bias modification training to assess the consequent effects on attentional bias change. While completing either an “attend threat” or “avoid threat” attention bias modification task, 77 volunteers (17–22 per group) received either active transcranial direct current stimulation of the left dorsolateral prefrontal cortex or a sham stimulation control condition. Results: Participants receiving active stimulation showed greater evidence of attentional bias acquisition in the targeted direction (toward or away from threat) compared with participants in the sham stimulation condition. Conclusions: Our findings provide the first experimental evidence that increasing activity in the dorsolateral prefrontal cortex leads to greater evidence of attention bias modification. This evidence confirms the role of these areas in facilitating change in the allocation of attention to threat. We believe this study provides a critical step in the translation of neuroimaging findings to novel neuromodulatory interventions capable of enhancing the treatment of emotional pathology.

    Related items

    Showing items related by title, author, creator and subject.

    • Attentional bias mediates the effect of neurostimulation on emotional vulnerability
      Chen, N.; Basanovic, J.; Notebaert, L.; MacLeod, C.; Clarke, Patrick (2017)
      Transcranial direct current stimulation (tDCS) is a neuromodulatory technique which has garnered recent interest in the potential treatment for emotion-based psychopathology. While accumulating evidence suggests that tDCS ...
    • The effects of attentional bias modification on emotion regulation
      Van Bockstaele, B.; Notebaert, L.; MacLeod, C.; Salemink, E.; Clarke, Patrick; Verschuere, B.; Bögels, S.; Wiers, R. (2019)
      © 2018 Elsevier Ltd Background and objectives: In two experiments, we investigated the effects of Attentional Bias Modification (ABM) on emotion regulation, i.e. the manner in which people influence emotional experiences. ...
    • It’s all about control: Memory bias in anxiety is restricted to threat cues that signal controllable danger
      Large, B.; MacLeod, C.; Clarke, Patrick; Notebaert, L. (2016)
      Although cognitive models of emotion propose that elevated trait anxiety may be associated with a memory bias for threatening information, evidence for such an anxiety-linked memory bias has been highly inconsistent. Given ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.