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    How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain?

    Access Status
    Fulltext not available
    Authors
    Henderson, L.A.
    Prieto, Flavia
    Date
    2016
    Type
    Journal Article
    
    Metadata
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    Citation
    Henderson, L.A. and Di Pietro, F. 2016. How do neuroanatomical changes in individuals with chronic pain result in the constant perception of pain? Pain management. 6 (2): pp. 147-159.
    Source Title
    Pain management
    DOI
    10.2217/pmt.15.67
    ISSN
    1758-1869
    Faculty
    Faculty of Health Sciences
    School
    School of Pharmacy and Biomedical Sciences
    URI
    http://hdl.handle.net/20.500.11937/79567
    Collection
    • Curtin Research Publications
    Abstract

    Since the advent of anatomical brain imaging analysis techniques, numerous reports have shown altered regional brain anatomy in individuals with various chronic pain conditions. While early reports of increased regional brain volumes in taxi drivers and pianists were simply interpreted as responses to excessive use, the mechanisms responsible for anatomical changes associated with chronic pain are not so straightforward. The main aim of this paper is to explore the potential underlying cellular changes responsible for change in gross brain anatomy in individuals with chronic pain, in particular pain following nervous system damage. Determining the basis of these changes may provide a platform for development of targeted, personalized and ultimately more effective treatment regimens.

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