Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Age-specific diastolic dysfunction improves prediction of symptomatic heart failure by Stage B heart failure

    80151.pdf (758.6Kb)
    Access Status
    Open access
    Authors
    Coller, J.M.
    Gong, F.F.
    McGrady, M.
    Jelinek, M.V.
    Castro, J.M.
    Boffa, U.
    Shiel, L.
    Liew, D.
    Stewart, S.
    Krum, H.
    Reid, Christopher
    Prior, D.L.
    Campbell, D.J.
    Date
    2019
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Coller, J.M. and Gong, F.F. and McGrady, M. and Jelinek, M.V. and Castro, J.M. and Boffa, U. and Shiel, L. et al. 2019. Age-specific diastolic dysfunction improves prediction of symptomatic heart failure by Stage B heart failure. ESC Heart Failure. 6 (4): pp. 747-757.
    Source Title
    ESC Heart Failure
    DOI
    10.1002/ehf2.12449
    ISSN
    2055-5822
    Faculty
    Faculty of Health Sciences
    School
    School of Public Health
    Funding and Sponsorship
    http://purl.org/au-research/grants/nhmrc/1044619
    http://purl.org/au-research/grants/nhmrc/1092642
    http://purl.org/au-research/grants/nhmrc/1136372
    http://purl.org/au-research/grants/nhmrc/1045862
    http://purl.org/au-research/grants/nhmrc/1041796
    http://purl.org/au-research/grants/nhmrc/559010
    http://purl.org/au-research/grants/nhmrc/395508
    http://purl.org/au-research/grants/nhmrc/620241
    http://purl.org/au-research/grants/nhmrc/519456
    Remarks

    © 2019 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology.

    URI
    http://hdl.handle.net/20.500.11937/80069
    Collection
    • Curtin Research Publications
    Abstract

    Aims: We investigated whether addition of diastolic dysfunction (DD) and longitudinal strain (LS) to Stage B heart failure (SBHF) criteria (structural or systolic abnormality) improves prediction of symptomatic HF in participants of the SCReening Evaluation of the Evolution of New Heart Failure study, a self-selected population at increased cardiovascular disease risk recruited from members of a health insurance fund in Melbourne and Shepparton, Australia. Both American Society of Echocardiography and European Association of Cardiovascular Imaging (ASE/EACVI) criteria and age-specific Atherosclerosis Risk in Communities (ARIC) study criteria, for SBHF and DD, and ARIC criteria for abnormal LS, were examined. Methods and results: Inclusion criteria were age ≥60 years with one or more of self-reported ischaemic or other heart disease, irregular or rapid heart rhythm, cerebrovascular disease, renal impairment, or treatment for hypertension or diabetes for ≥2 years. Exclusion criteria were known HF, or ejection fraction <50% or >mild valve abnormality detected on previous echocardiography or other imaging. Echocardiography was performed in 3190 participants who were followed for a median of 3.9 (interquartile range: 3.4, 4.5) years after echocardiography. Symptomatic HF was diagnosed in 139 participants at a median of 3.1 (interquartile range: 2.1, 3.9) years after echocardiography. ARIC structural, systolic, and diastolic abnormalities predicted HF in univariate and multivariable proportional hazards analyses, whereas ASE/EACVI structural and systolic, but not diastolic, abnormalities predicted HF. ARIC and ASE/EACVI SBHF criteria predicted HF with sensitivities of 81% and 55%, specificities of 39% and 76%, and C statistics of 0.60 (95% confidence interval: 0.57, 0.64) and 0.66 (0.61, 0.71), respectively. Adding ARIC DD to SBHF increased sensitivity to 94% with specificity of 24% and C statistic of 0.59 (0.57, 0.61), whereas addition of ASE/EACVI DD to SBHF increased sensitivity to 97% but reduced specificity to 9% and the C statistic to 0.52 (0.50, 0.54, P < 0.0001). Addition of LS to ARIC or ASE/EACVI SBHF criteria had minimal impact on prediction of HF. Conclusions: Age-specific ARIC DD criteria, but not ASE/EACVI DD criteria, predicted symptomatic HF, and addition of age-specific ARIC DD criteria to ARIC SBHF criteria improved prediction of symptomatic HF in asymptomatic individuals with cardiovascular disease risk factors. Addition of LS to ASE/EACVI or ARIC SBHF criteria did not improve prediction of symptomatic HF.

    Related items

    Showing items related by title, author, creator and subject.

    • Prediction of heart failure by serum amino-terminal-pro-b-type natriuretic peptide (nt-probnp): an interim analysis of the screening evaluation of the evolution of new heart failure (screen-hf) study
      Campbell, D.; McGrady, M.; Prior, D.; Coller, J.; Sheil, L.; Boffa, U.; Wolfe, R.; Reid, Christopher; Krum, H. (2015)
      Serum NT-proBNP level predicts heart failure. The SCREEN-HF study is a community-based cohort study that aims to identify an appropriate threshold NT-proBNP level for stratification of individuals into high and low risk ...
    • Prediction of incident heart failure by serum amino-terminal pro-B-type natriuretic peptide level in a community-based cohort
      Campbell, D.; Gong, F.; Jelinek, M.; Castro, J.; Coller, J.; McGrady, M.; Boffa, U.; Shiel, L.; Wang, B.; Liew, D.; Wolfe, R.; Stewart, S.; Owen, A.; Krum, H.; Reid, Christopher; Prior, D. (2019)
      Aims: We investigated which serum amino-terminal pro-B-type-natriuretic peptide (NT-proBNP) levels inform heart failure (HF) risk in a community-based population at increased cardiovascular disease (CVD) risk. Methods and ...
    • Risk factor management in a contemporary Australian population at increased cardiovascular disease risk
      Campbell, D.; Coller, J.; Gong, F.; McGrady, M.; Prior, D.; Boffa, U.; Shiel, L.; Liew, D.; Wolfe, R.; Owen, A.; Krum, H.; Reid, Christopher (2018)
      Background: Effective management of cardiovascular and chronic kidney disease risk factors offers longer, healthier lives and savings in healthcare. Aim: To examine risk factor management in participants of the SCReening ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.