Immunogenicity of the inactivated influenza vaccine in children who have undergone autologous stem cell transplant
MetadataShow full item record
Funding and Sponsorship
To the Editor: Autologous stem cell transplant (SCT) is an upfront therapeutic modality for children with malignancies such as high-risk neuroblastoma and atypical teratoid rhabdoid tumour and a salvage option for children with lymphoma and a variety of solid tumours. The administration of highdose myeloablative chemotherapy during conditioning increases vulnerability to infection. Influenza infection can result in significant complications, in particular progression to pneumonia, in patients who have undergone autologous SCT [1, 2]. Influenza vaccination is recommended to prevent infection in children following autologous SCT , however, there is limited evidence regarding its benefit in this population . Due to the paucity of data, we performed a prospective multicentre study to evaluate the immunogenicity of the seasonal inactivated influenza vaccine in children who have undergone autologous SCT compared with healthy matched controls.
Showing items related by title, author, creator and subject.
Comparison between Nasal Swabs and Nasopharyngeal Aspirates for, and Effect of Time in Transit on, Isolation of Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and Moraxella catarrhalisCarville, K.; Bowman, J.; Lehmann, Deborah; Riley, T. (2007)pmc logo image Logo of jcm Note: Performing your original search, comparison nasal swabs lehmann, in PubMed Central will retrieve 7 citations. Journal List > J Clin Microbiol > v.45(1); Jan 2007 Abstract ...
Why do we not want to recommend influenza vaccination to young children? A qualitative study of Australian parents and primary care providersBiezen, R.; Grando, D.; Mazza, D.; Brijnath, Bianca (2018)© 2018 Elsevier Ltd. Introduction: Influenza vaccination has been shown to be safe and effective against influenza and in the prevention of complicating secondary respiratory illnesses. However, its uptake in young children ...
The impact of pandemic A(H1N1)pdm09 influenza and vaccine-associated adverse events on parental attitudes and influenza vaccine uptake in young childrenBlyth, C.; Richmond, P.; Jacoby, P.; Thornton, P.; Regan, Annette; Robins, C.; Kelly, H.; Smith, D.; Effler, P. (2014)Introduction: Parental attitudes towards vaccination significantly influence vaccine uptake. The A(H1N1)pdm09 influenza pandemic was followed in 2010 by an unprecedented increase in febrile reactions in children receiving ...