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    Marine pseudovibrio sp. as a novel source of antimicrobials

    Access Status
    Open access via publisher
    Authors
    Crowley, S.
    O'Gara, Fergal
    O'Sullivan, O.
    Cotter, P.
    Dobson, A.
    Date
    2014
    Type
    Journal Article
    
    Metadata
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    Citation
    Crowley, S. and O'Gara, F. and O'Sullivan, O. and Cotter, P. and Dobson, A. 2014. Marine pseudovibrio sp. as a novel source of antimicrobials. Marine Drugs. 12 (12): pp. 5916-5929.
    Source Title
    Marine Drugs
    DOI
    10.3390/md12125916
    School
    School of Biomedical Sciences
    URI
    http://hdl.handle.net/20.500.11937/8209
    Collection
    • Curtin Research Publications
    Abstract

    Antibiotic resistance among pathogenic microorganisms is becoming ever more common. Unfortunately, the development of new antibiotics which may combat resistance has decreased. Recently, however the oceans and the marine animals that reside there have received increased attention as a potential source for natural product discovery. Many marine eukaryotes interact and form close associations with microorganisms that inhabit their surfaces, many of which can inhibit the attachment, growth or survival of competitor species. It is the bioactive compounds responsible for the inhibition that is of interest to researchers on the hunt for novel bioactives. The genus Pseudovibrio has been repeatedly identified from the bacterial communities isolated from marine surfaces. In addition, antimicrobial activity assays have demonstrated significant antimicrobial producing capabilities throughout the genus. This review will describe the potency, spectrum and possible novelty of the compounds produced by these bacteria, while highlighting the capacity for this genus to produce natural antimicrobial compounds which could be employed to control undesirable bacteria in the healthcare and food production sectors.

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