The impact of Vitamin D on Muscle Metabolism, Bioenergetic Responses and Exercise Performance
Access Status
Open access
Authors
Romeu Montenegro, Karina
Date
2021Supervisor
Philip Newsholme
Rodrigo Carlessi
Type
Thesis
Award
PhD
Metadata
Show full item recordFaculty
Health Sciences
School
School of Pharmacy and Biomedical Sciences
Collection
Abstract
This PhD thesis describes the effects of Vitamin D on skeletal muscle and includes details of two main research projects. The first study validated a physiologically significant effect of VitD3 in proliferation, differentiation, protein synthesis and mitochondrial metabolism in primary human skeletal muscle cells, in cell culture. The second study demonstrated that VitD3 supplementation does not result in additional benefits on muscle strength, power, resting metabolic rate and body composition in VitD sufficient physically active adults.
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