Platinum(II) Complexes for Biological Applications

Grady, Thomas James

Grady T 2021.pdf (5.201Mb)

Access Status

Open access

Authors

Grady, Thomas James

Date

2021

Supervisor

Max Massi

Mark Ogden

Type

Thesis

Award

MRes

Metadata

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Faculty

Science and Engineering

School

School of Molecular and Life Sciences

URI

http://hdl.handle.net/20.500.11937/82825

Collection

Curtin Theses

Abstract

In this study the synthesis, photophysical properties, and potential biological applications of a range of platinum(II) complexes were investigated. A family of platinum(II) complexes bearing cyclometallated NHC ligands alongside were developed and found to have favourable photophysical properties. Two palladium analogues of platinum(II) complexes were reported and investigated for antimicrobial activity. Finally, the synthesis of a terdentate C^C^N coordinated platinum(II) complexes was investigated, and a number of significant challenges identified.