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dc.contributor.authorAhmad, T.
dc.contributor.authorJadoon, M.A.
dc.contributor.authorKhan, M.
dc.contributor.authorHaroon
dc.contributor.authorKhan, M.M.
dc.contributor.authorHussain, A.
dc.contributor.authorMusa, T.H.
dc.contributor.authorWaqar, M.
dc.contributor.authorEjeta, E.
dc.contributor.authorKarami, M.
dc.contributor.authorAlene, Kefyalew
dc.contributor.authorJin, H.
dc.contributor.authorAhmad, T.
dc.date.accessioned2021-11-17T09:47:00Z
dc.date.available2021-11-17T09:47:00Z
dc.date.issued2020
dc.identifier.citationAhmad, T. and Jadoon, M.A. and Khan, M. and Haroon and Khan, M.M. and Hussain, A. and Musa, T.H. et al. 2020. Treatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan. BMC Infectious Diseases. 20 (1): Article No. 463.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/86479
dc.identifier.doi10.1186/s12879-020-05184-3
dc.description.abstract

Background: Globally, tuberculosis (TB) remains the leading cause of death from a single infectious disease. TB treatment outcome is an important indicator for the effectiveness of a national TB control program. This study aimed to assess treatment outcomes of TB patients and its determinants in Batkhela, Khyber Pakhtunkhwa, Pakistan. Methods: A retrospective cohort study was designed using all TB patients who were enrolled at District Head Quarter (DHQ) Hospital Batkhela, Pakistan, from January 2011 to December 2014. A binary logistic regression models were used to identify factors associated with successful TB treatment outcomes defined as the sum of cure and completed treatment. Results: A total of 515 TB patients were registered, of which 237 (46%) were males and 278 (53.98%) females. Of all patients, 234 (45.44%) were cured and 210 (40.77%) completed treatment. The overall treatment success rate was 444 (86.21%). Age 0-20 years (adjusted odds ratio, AOR = 3.47; 95% confidence interval, CI) = 1.54-7.81; P = 0.003), smear-positive pulmonary TB (AOR) = 3.58; 95% CI = 1.89-6.78; P = < 0.001), treatment category (AOR = 4.71; 95% CI = 1.17-18.97; P = 0.029), and year of enrollment 2012 (AOR = 6.26; 95% CI = 2.52-15.59; P = < 0.001) were significantly associated with successful treatment outcome. Conclusions: The overall treatment success rate is satisfactory but still need to be improved to achieve the international targeted treatment outcome. Type of TB, age, treatment category, and year of enrollment were significantly associated with successful treatment outcomes.

dc.languageEnglish
dc.publisherBMC
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectInfectious Diseases
dc.subjectTuberculosis
dc.subjectTreatment outcome
dc.subjectPakistan
dc.subjectSHORT-COURSE DOTS
dc.subjectPULMONARY TUBERCULOSIS
dc.subjectDISTRICT MALAKAND
dc.subjectPOPULATION
dc.subjectPREVALENCE
dc.subjectSTILL
dc.titleTreatment outcomes of patients with tuberculosis in war affected region of Khyber Pakhtunkhwa, Pakistan
dc.typeJournal Article
dcterms.source.volume20
dcterms.source.number1
dcterms.source.issn1471-2334
dcterms.source.titleBMC Infectious Diseases
dc.date.updated2021-11-17T09:46:58Z
curtin.note

© The Author(s). 2020 Published in BMC Infectious Diseases. This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/. Please refer to the licence to obtain terms for any further reuse or distribution of this work.

curtin.departmentCurtin School of Population Health
curtin.accessStatusOpen access
curtin.facultyFaculty of Health Sciences
curtin.contributor.orcidAlene, Kefyalew [0000-0002-1904-4682]
curtin.contributor.researcheridAlene, Kefyalew [V-8240-2018]
curtin.identifier.article-numberARTN 463
dcterms.source.eissn1471-2334
curtin.contributor.scopusauthoridAlene, Kefyalew [57202583764]


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