Show simple item record

dc.contributor.authorShirolkar, Gayatri Dhananjay
dc.contributor.supervisorNina Tirnitz-Parkeren_US
dc.date.accessioned2021-11-25T05:20:03Z
dc.date.available2021-11-25T05:20:03Z
dc.date.issued2021en_US
dc.identifier.urihttp://hdl.handle.net/20.500.11937/86615
dc.description.abstract

This study established a regulatory role for the Wnt/ß-catenin pathway in liver progenitor cells (LPCs) in cell culture and in vivo models of non-alcoholic fatty liver disease and demonstrated a significant potential for therapeutic targeting of LPCs with the Wnt inhibitor PRI-724 to inhibit chronic liver disease progression.

en_US
dc.publisherCurtin Universityen_US
dc.titleThe role of Wnt/β-catenin signalling in the regulation of liver progenitor cell responses in non-alcoholic fatty liver diseaseen_US
dc.typeThesisen_US
dcterms.educationLevelPhDen_US
curtin.departmentCurtin Medical Schoolen_US
curtin.accessStatusOpen accessen_US
curtin.facultyHealth Sciencesen_US
curtin.contributor.orcidShirolkar, Gayatri Dhananjay [0000-0001-7728-4708]en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record