Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections
| dc.contributor.author | Ravensdale, Joshua Thomas | |
| dc.contributor.supervisor | Dr Frances O’Brien | |
| dc.contributor.supervisor | Prof. Elizabeth Watkin | |
| dc.contributor.supervisor | Dr Keith Gregg | |
| dc.date.accessioned | 2017-01-30T09:54:54Z | |
| dc.date.available | 2017-01-30T09:54:54Z | |
| dc.date.created | 2015-12-10T06:07:58Z | |
| dc.date.issued | 2015 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/870 | |
| dc.description.abstract |
In this study, resistance towards antimicrobial peptides developed rapidly in MRSA, but resistance was mitigated by controlling the environment in which the cells are treated. Resistance was not stable in a population and seemed to sensitise some cells to certain antibiotics. Antibacterial peptides enhanced the bactericidal effectiveness of an antibacterial gauze when used in tandem with a wetting agent and lysozyme. Results from this study suggest antibacterial peptides may have clinical applications as topical therapeutics. | |
| dc.language | en | |
| dc.publisher | Curtin University | |
| dc.title | Investigations into the therapeutic potential of antimicrobial peptides: applications for treating topical Staphylococcus aureus infections | |
| dc.type | Thesis | |
| dcterms.educationLevel | PhD | |
| curtin.department | School of Biomedical Sciences | |
| curtin.accessStatus | Open access |