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    The Micro- and Nano-scale Structure of the Most Superficial Layer of Articular Cartilage

    Boyanich RL 2022 Public.pdf (1.303Mb)
    Access Status
    Open access
    Authors
    Boyanich, Rebecca Lee
    Date
    2022
    Supervisor
    Garry Allison
    Type
    Thesis
    Award
    MPhil
    
    Metadata
    Show full item record
    Faculty
    Science and Engineering
    School
    School of Civil and Mechanical Engineering
    URI
    http://hdl.handle.net/20.500.11937/88897
    Collection
    • Curtin Theses
    Abstract

    This dissertation illustrates the three-dimensional structure and composition of the most superficial layer of healthy sheep articular cartilage to gain understanding of the role of this layer in the tissue’s function. This was achieved by isolating the layer from the underlying cartilage to study using confocal and atomic force microscopy. The imaging techniques studied the microstructure of the most superficial layer. This knowledge can advance our understanding of the aetiology of osteoarthritis and aid the development of tissue regenerative therapies and diagnostic techniques.

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