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dc.contributor.authorBelus, J.M.
dc.contributor.authorJoska, J.A.
dc.contributor.authorBronsteyn, Y.
dc.contributor.authorRose, A.L.
dc.contributor.authorAndersen, L.S.
dc.contributor.authorRegenauer, K.S.
dc.contributor.authorMyers-Franchi, Bronwyn
dc.contributor.authorHahn, J.A.
dc.contributor.authorOrrell, C.
dc.contributor.authorSafren, S.A.
dc.contributor.authorMagidson, J.F.
dc.date.accessioned2022-10-23T20:25:43Z
dc.date.available2022-10-23T20:25:43Z
dc.date.issued2022
dc.identifier.citationBelus, J.M. and Joska, J.A. and Bronsteyn, Y. and Rose, A.L. and Andersen, L.S. and Regenauer, K.S. and Myers, B. et al. 2022. Gender Moderates Results of a Randomized Clinical Trial for the Khanya Intervention for Substance Use and ART Adherence in HIV Care in South Africa. AIDS and Behavior. 26 (11): pp. 3630-3641.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/89483
dc.identifier.doi10.1007/s10461-022-03765-8
dc.description.abstract

Little is known about gender effects of alcohol and drug use (AOD) among people living with HIV (PLWH) in resource-limited settings. Using multilevel models, we tested whether gender moderated the effect of Khanya, a cognitive-behavioral therapy-based intervention addressing antiretroviral (ART) adherence and AOD reduction. We enrolled 61 participants from HIV care and examined outcomes at 3- and 6-months compared to enhanced treatment as usual (ETAU). Gender significantly moderated the effect of Khanya on ART adherence (measured using electronically-monitored and biomarker-confirmed adherence), such that women in Khanya had significantly lower ART adherence compared to men in Khanya; no gender differences were found for AOD outcomes. Exploratory trajectory analyses showed men in Khanya and both genders in ETAU had significant reductions in at least one AOD outcome; women in Khanya did not. More research is needed to understand whether a gender lens can support behavioral interventions for PLWH with AOD. Trial registry ClinicalTrials.gov identifier: NCT03529409. Trial registered on May 18, 2018.

dc.languageEnglish
dc.publisherSPRINGER/PLENUM PUBLISHERS
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectScience & Technology
dc.subjectSocial Sciences
dc.subjectLife Sciences & Biomedicine
dc.subjectPublic, Environmental & Occupational Health
dc.subjectSocial Sciences, Biomedical
dc.subjectBiomedical Social Sciences
dc.subjectART adherence
dc.subjectSubstance use
dc.subjectBehavioral intervention
dc.subjectGender differences
dc.subjectSouth Africa
dc.subjectINTIMATE PARTNER VIOLENCE
dc.subjectALCOHOL-USE
dc.subjectCAPE-TOWN
dc.subjectDRINKING
dc.subjectNONADHERENCE
dc.subjectDISEASE
dc.subjectHEALTH
dc.subjectDRUGS
dc.titleGender Moderates Results of a Randomized Clinical Trial for the Khanya Intervention for Substance Use and ART Adherence in HIV Care in South Africa
dc.typeJournal Article
dcterms.source.volume26
dcterms.source.number11
dcterms.source.startPage3630
dcterms.source.endPage3641
dcterms.source.issn1090-7165
dcterms.source.titleAIDS and Behavior
dc.date.updated2022-10-23T20:25:40Z
curtin.departmentEnAble Institute
curtin.accessStatusOpen access
curtin.facultyFaculty of Health Sciences
dcterms.source.eissn1573-3254
curtin.contributor.scopusauthoridMyers-Franchi, Bronwyn [7202684194]


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